Candesartan Cilexetil Impurity 24 CAS 139481-28-0
| CAS No. | 139481-28-0 |
| Molecular Formula | C22H17N3O4 |
| Molecular Weight | 387.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Candesartan Cilexetil Impurity 24 (CAS 139481-28-0) is a certified pharmaceutical impurity reference standard with the molecular formula C22H17N3O4 and a molecular weight of 387.39 g/mol.
Based on its molecular formula C22H17N3O4, Candesartan Cilexetil Impurity 24 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 387.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H17N3O4 |
| Molecular Weight | 387.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 3 |
Related Candesartan Standards
- Candesartan Cilexetil Impurity 39 (CAS CATO-C4X-123439)
- Candesartan Cilexetil Impurity 38 (CAS CATO-C4X-123438)
- Candesartan Cilexetil Impurity 37 (CAS 147404-74-8)
- Candesartan impurity 4 (CAS CATO-C4X-15724)
- Candesartan Cilexetil Impurity 14 (CAS 136304-78-4)
- Candesartan Cilexetil Impurity 40 (CAS CATO-C4X-123440)
- Candesartan Cilexetil Impurity 46 (CAS 1821386-35-9)
- Candesartan Ethyl Ester Desethyl Analog (CAS 1225044-20-1)
Recommended Standards
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