8-Fluoro-2-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one CAS 1267701-87-0
| CAS No. | 1267701-87-0 |
| Molecular Formula | C9H8FNO2 |
| Molecular Weight | 181.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Fluoro-2-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one.
8-Fluoro-2-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one (CAS 1267701-87-0), molecular formula C9H8FNO2 and molecular weight 181.16 g/mol, is a CATO reference standard with documented purity and traceability.
8-Fluoro-2-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one (C9H8FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-Fluoro-2-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8FNO2 |
| Molecular Weight | 181.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- (E)-Ethyl 3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate (CAS 55520-60-0)
- Ceftazidime Impurity 99 (CAS CATO-C4X-121299)
- (R)-N-Ethyl-N-(pyrrolidin-2-ylmethyl)ethanamine (CAS 1604338-03-5)
- 1-[2-(2-Phenylmethoxyethoxy)ethoxy]-4-(2,4,4-trimethylpentan-2-yl)benzene (CAS 1797129-92-0)
- 2-(Trifluoromethyl)pyrido[2,3-d]pyrimidin-4(3H)-one (CAS 338739-97-2)
- Dimethyl 6,6'-bis(bromomethyl)-[2,2'-bipyridine]-4,4'-dicarboxylate (CAS 117330-41-3)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
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