Gemcitabine Impurity 27 CAS 1268237-46-2
| CAS No. | 1268237-46-2 |
| Molecular Formula | C23H19F2N3O6 |
| Molecular Weight | 471.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 471.41 g/mol gives Gemcitabine Impurity 27 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Gemcitabine Impurity 27 (CAS 1268237-46-2), a pharmacopoeial impurity reference standard (molecular formula C23H19F2N3O6, MW 471.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C23H19F2N3O6, Gemcitabine Impurity 27 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 471.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Gemcitabine Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H19F2N3O6 |
| Molecular Weight | 471.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Gemcitabine Standards
- Gemcitabine Impurity 11 (CAS 134790-39-9)
- Gemcitabine Impurity 16 (CAS CATO-C4X-137216)
- Gemcitabine Impurity 28 (CAS 134790-40-2)
- Gemcitabine Impurity 38 (CAS CATO-C4X-137238)
- Gemcitabine Impurity 30 (CAS 143157-27-1)
- Gemcitabine Impurity 34 (CAS CATO-C4X-137234)
- Gemcitabine Impurity 35 (CAS CATO-C4X-137235)
- Gemcitabine Impurity 10 (CAS 122111-11-9)
Recommended Standards
- N-(2-bromophenyl)-2-((5-cyclohexyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332872-86-3)
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- 3-Sialylgalactose sodium salt (CAS 83563-61-5)
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- tert-butyl 3-methyl-1,4-diazepane-1-carboxylate (CAS 194032-35-4)
- (2E,8E)-Deca-2,8-dien-4,6-diyn-1-yl acetate (CAS 1002-64-8)
- 5-(2,4-Dichlorobenzoyl)-N-phenyl-1,3-thiazol-2-amine (CAS 339008-11-6)
- 3-([1,1'-Biphenyl]-4-yl)-1H-1,2,4-triazol-5-amine (CAS 168893-47-8)
- 3-Iodotoluene (CAS 625-95-6)
- Methyl (E)-2-(2-(dimethylamino)vinyl)-6-(4-methoxyphenyl)-5-oxo-5,6-dihydro-1,6-naphthyridine-3-carboxylate (CAS 1374510-93-6)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com