1-(5-Bromo-2-chlorobenzoyl)pyrrolidine-2-carboxamide CAS 1268326-79-9
| CAS No. | 1268326-79-9 |
| Molecular Formula | C12H12BrClN2O2 |
| Molecular Weight | 331.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(5-Bromo-2-chlorobenzoyl)pyrrolidine-2-carboxamide (CAS 1268326-79-9), molecular formula C12H12BrClN2O2 and molecular weight 331.59 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(5-Bromo-2-chlorobenzoyl)pyrrolidine-2-carboxamide (C12H12BrClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(5-Bromo-2-chlorobenzoyl)pyrrolidine-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12BrClN2O2 |
| Molecular Weight | 331.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- tert-butyl 5-bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylate (CAS 1207624-04-1)
- Ketoconazole Impurity 20 (CAS CATO-C4X-147220)
- N-(4-Amino-5-chloro-2-hydroxyphenyl)-3,4-dichlorobenzamide (CAS 95709-82-3)
- Methyl 6-amino-5-(2,3,5-trichlorophenyl)picolinate (CAS 875051-79-9)
- Tert-butyl (3-isobutyramidophenyl)carbamate (CAS 925610-53-3)
- 1,5-Dibromo-3-(difluoromethyl)-2-fluorobenzene (CAS 1803776-87-5)
- m-Cymen-6-ol (CAS 1740-97-2)
- 5-Bromobenzo[d]oxazole-2-carboxylic acid (CAS 944898-52-6)
- 3-(o-Tolyl)pyridin-4-amine (CAS 1341622-75-0)
- methyl 3-(2-nitroethyl)-1H-indole-4-carboxylate (CAS 123883-35-2)
- DMABA-d (CAS 1175002-03-5)
- 1-{8-azabicyclo[3.2.1]octan-3-yl}-3,3-dimethylurea hydrochloride (CAS 2060042-85-3)
- Phytomenadione/Vitamin K1 Impurity 127 (CAS CATO-C4X-2207127)
- Characteristic MSH-Tetrapeptide (CAS 4289-02-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com