2-Methoxy-4-methylthiazole-5-carboxylic acid CAS 126909-38-4
| CAS No. | 126909-38-4 |
| Molecular Formula | C6H7NO3S |
| Molecular Weight | 173.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Methoxy-4-methylthiazole-5-carboxylic acid (CAS 126909-38-4) is a high-purity analytical reference standard with the molecular formula C6H7NO3S and a molecular weight of 173.19 g/mol.
The molecular framework of 2-Methoxy-4-methylthiazole-5-carboxylic acid (C6H7NO3S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-Methoxy-4-methylthiazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H7NO3S |
| Molecular Weight | 173.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methoxy Standards
- 4-Methoxy-2-methylthiazole-5-carboxylic acid (CAS 851755-42-5)
- 5-Methoxy-2,3-dihydro-1H-indene-1-carbonitrile (CAS 102035-37-0)
- 8-Methoxy-3-methylisoquinoline (CAS 1037219-57-0)
- 6-Methoxy-2-methylquinoline (CAS 1078-28-0)
- 4-methoxy-1-methylpiperidine-4-carboxylic acid (CAS 1082040-35-4)
- 8-Methoxy-3-methylquinoline (CAS 112955-06-3)
- 5-methoxy-2-methylpyridine-3-carboxylic acid (CAS 1174402-76-6)
- 2-Methoxy-N-(tetrahydro-2H-pyran-4-yl)acetamide (CAS 1186047-29-9)
Recommended Standards
- 4-(Methylsulfonyl)pyridin-2(1H)-one (CAS 1268519-33-0)
- Ethyl 4-hydroxythiazole-2-carboxylate (CAS 1289217-98-6)
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- Pyridin-2-ylmethanesulfonic acid (CAS 132685-16-6)
- Sudan Yellow 3G (CAS 4314-14-1)
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- Furo[2,3-b]pyridine-5-carboxamide (CAS 220957-44-8)
- Gemcitabine Impurity 17 (CAS 197452-15-6)
- 1-Isopropyl-1H-indole-6-carbaldehyde (CAS 921602-58-6)
- 6,8-Dichloro-3-(2-chlorobenzyl)quinazolin-4(3H)-one (CAS 302913-48-0)
- 2-Azaspiro[4.5]Decan-4-ol (CAS 1779940-17-8)
- 2-bromo-6-ethoxy-4-formylphenyl benzoate (CAS 431935-02-3)
- 2-Amino-4-(4-butylphenyl)thiophene-3-carbonitrile (CAS 519016-85-4)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
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