Gemcitabine Impurity 17 CAS 197452-15-6
| CAS No. | 197452-15-6 |
| Molecular Formula | C19H14F2O6 |
| Molecular Weight | 376.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Gemcitabine Impurity 17 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Gemcitabine Impurity 17 (CAS 197452-15-6), molecular formula C19H14F2O6 and molecular weight 376.31 g/mol, is a CATO reference standard with documented purity and traceability.
Gemcitabine Impurity 17 (C19H14F2O6) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Gemcitabine Impurity 17 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14F2O6 |
| Molecular Weight | 376.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
| Halogen Content | F-containing |
Related Gemcitabine Standards
- Gemcitabine Impurity 10 (CAS 1217452-91-9)
- Gemcitabine Impurity 29 (CAS 122111-02-8)
- Gemcitabine Impurity 32 (CAS 122111-01-7)
- Gemcitabine Impurity 16 (CAS 1173824-58-2)
- Gemcitabine Impurity 11 (CAS 143157-25-9)
- Gemcitabine Impurity 9 (CAS 143157-22-6)
- Gemcitabine Impurity 31 (CAS 142816-70-4)
- Gemcitabine Impurity 5 (CAS 2174019-90-8)
Recommended Standards
- N-methyl-4-(4-nitro-2-(trifluoromethyl)phenoxy)benzenesulfonamide (CAS 1858250-61-9)
- (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methyltetrahydrofuran-3-ol (CAS 26383-05-1)
- 1,3,4-Triphenyl-1H-1,2,4-triazole-5(4H)-selenone (CAS 185761-76-6)
- (3-Bromophenyl)(3-(thiomorpholinomethyl)phenyl)methanone (CAS 898763-00-3)
- 2-(2-Phenylphenoxy)ethanethioamide (CAS 927994-99-8)
- 5-Chloro-N-cyclopropyl-2-nitrobenzamide (CAS 355383-67-4)
- tert-butyl N-[trans-4-hydroxy-4-methylcyclohexyl]carbamate (CAS 233764-31-3)
- 2-((4-Methylpiperidin-1-yl)methyl)benzaldehyde (CAS 1443348-06-8)
- 5-Bromo-4-ethylpyridin-2-ol (CAS 1369325-65-4)
- (2-Bromophenyl)(3-methoxyphenyl)methanol (CAS 634152-97-9)
- 1,4-Dimethoxy-2-methyl-5-nitrobenzene (CAS 32185-64-1)
- 1-(5-((4-Chlorophenyl)thio)-4-nitrothiophen-2-yl)ethan-1-one (CAS 882256-99-7)
- [(3-Methylphenyl)methyl](prop-2-en-1-yl)amine hydrochloride (CAS 1240568-87-9)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com