5-Chloro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile CAS 1269294-29-2
| CAS No. | 1269294-29-2 |
| Molecular Formula | C8H4ClN5 |
| Molecular Weight | 205.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 5-Chloro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile (CAS 1269294-29-2), a certified reference material (molecular formula C8H4ClN5, MW 205.60 g/mol) for analytical method development and quality control.
Based on its molecular formula C8H4ClN5, 5-Chloro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 205.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H4ClN5 |
| Molecular Weight | 205.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- 3-(4-Chloro-3-nitro-1h-pyrazol-1-yl)propan-1-ol (CAS 1006950-47-5)
- 6-Chloro-2-hydroxy-1,8-naphthyridine-3-carbonitrile (CAS 1330583-66-8)
- Methyl 3-chloro-1-(methoxymethyl)-1H-1,2,4-triazole-5-carboxylate (CAS 1807988-24-4)
- 5-Chloro-2-(1H-tetrazol-1-yl)benzonitrile (CAS 449758-28-5)
- 6-Chloro-2-oxo-2h-chromene-3-carbonitrile (CAS 28447-81-6)
- 6-Chloro-4-oxo-4H-chromene-3-carbonitrile (CAS 50743-20-9)
- 5-Chloro-6-(1,1-difluoroethyl)nicotinaldehyde (CAS 1429182-80-8)
- 4-Chloro-6-(difluoromethyl)-2-methylnicotinaldehyde (CAS 1805178-02-2)
Recommended Standards
- 4-Chloropyrido[3,2:4,5]furo[3,2-d]pyrimidine (CAS 1198569-37-7)
- (S)-Methyl 2-(chlorocarbonyl)-5-oxopyrrolidine-1-carboxylate (CAS 172988-55-5)
- N-Acetyl-4-chloro-3,5-difluoroaniline (CAS 457-30-7)
- N-(2-Chloro-4,5-difluorophenyl)acetamide (CAS 325-77-9)
- O-(3,5-Dichlorobenzyl)hydroxylamine (CAS 755740-10-4)
- (4-(Methylamino)phenyl)methanol (CAS 181819-75-0)
- 4-Bromo-2-fluorobenzyl alcohol (CAS 188582-62-9)
- (Dichlorofluoromethyl)cyclohexane (CAS 247170-24-7)
- Ethyl 3-isobutyl-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylate (CAS 457910-74-6)
- Ethyl 1-(3-(2-(2-oxo-1,2-dihydropyridine-3-carboxamido)thiazol-4-yl)propanoyl)piperidine-4-carboxylate (CAS 1040666-78-1)
- Olmesartan impurity 103 (CAS 93641-16-8)
- methyl 1-acetyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylate (CAS 1864073-23-3)
- Benzhydrol-d10 (CAS 74563-01-2)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
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