Olmesartan impurity 103 CAS 93641-16-8
| CAS No. | 93641-16-8 |
| Molecular Formula | C17H14F2O2 |
| Molecular Weight | 288.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Olmesartan impurity 103 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Olmesartan impurity 103 (CAS 93641-16-8), a pharmacopoeial impurity reference standard (molecular formula C17H14F2O2, MW 288.29 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Olmesartan impurity 103 (C17H14F2O2) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C17H14F2O2 |
| Molecular Weight | 288.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | F-containing |
Related Olmesartan Standards
- Olmesartan Impurity 45 (CAS 866721-92-8)
- Olmesartan Impurity 29 (CAS 76-83-5)
- Olmesartan Impurity 59 (CAS 971-85-7)
- Olmesartan Impurity 76 (CAS 161952-66-5)
- Olmesartan impurity 88 (CAS CATO-C4X-109788)
- Olmesartan Impurity 57 (CAS CATO-C4X-109757)
- Olmesartan Impurity 32 (CAS 1092980-85-2)
- Olmesartan Impurity 36 (CAS 1092980-84-1)
Recommended Standards
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