4,7-Dichloro-2-(pyridin-2-yl)quinazoline CAS 1269703-91-4
| CAS No. | 1269703-91-4 |
| Molecular Formula | C13H7Cl2N3 |
| Molecular Weight | 276.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 276.12 g/mol gives 4,7-Dichloro-2-(pyridin-2-yl)quinazoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4,7-Dichloro-2-(pyridin-2-yl)quinazoline (CAS 1269703-91-4), a certified reference material (molecular formula C13H7Cl2N3, MW 276.12 g/mol) for analytical method development and quality control.
The molecular framework of 4,7-Dichloro-2-(pyridin-2-yl)quinazoline (C13H7Cl2N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,7-Dichloro-2-(pyridin-2-yl)quinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H7Cl2N3 |
| Molecular Weight | 276.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloro Standards
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Recommended Standards
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- dBET1 (CAS 1799711-21-9)
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- 5-Hydroxy-7-methoxy-2,2-dimethylhepta-4,6-dien-3-one (CAS 74628-10-7)
- 3-Chloro-6-(prop-2-yn-1-ylamino)picolinic acid (CAS 1020948-43-9)
- Glipizide Impurity 34 (CAS 14511-59-2)
- Aripiprazole Impurity 78 (CAS CATO-C4X-100878)
- (E)-4-(2-(2-(4-(tert-butyl)phenoxy)acetyl)hydrazinyl)-4-oxobut-2-enoic acid (CAS 501106-52-1)
- 4-Nitrosobenzonitrile (CAS 31125-07-2)
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