4-Chloro-1-(3-fluorophenyl)-6-methyl-1H-pyrazolo[3,4-d]pyrimidine CAS 1269705-39-6
| CAS No. | 1269705-39-6 |
| Molecular Formula | C12H8ClFN4 |
| Molecular Weight | 262.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Chloro-1-(3-fluorophenyl)-6-methyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1269705-39-6) is a high-purity analytical reference standard with the molecular formula C12H8ClFN4 and a molecular weight of 262.67 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 4-Chloro-1-(3-fluorophenyl)-6-methyl-1H-pyrazolo[3,4-d]pyrimidine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 262.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8ClFN4 |
| Molecular Weight | 262.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-9-(2-fluorobenzyl)-9h-purine (CAS 101155-08-2)
- 4-chloro-1-(4-fluorophenyl)-6-methyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1097095-32-3)
- N-(3-Chloro-4-fluorophenyl)-1H-pyrazolo[4,3-b]pyridin-3-amine (CAS 1330624-42-4)
- 4-Chloro-1-(3-fluoro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1416341-19-9)
- 6-Chloro-2-(4-fluoro-1H-indol-2-yl)pyridin-3-ol (CAS 1426942-84-8)
- 2-(2-Chloro-4-fluorophenyl)benzo[d]oxazol-5-amine (CAS 313527-40-1)
- 2-(3-Chloro-4-fluorophenyl)benzo[d]oxazol-5-amine (CAS 954815-17-9)
- 6-Chloro-3-oxo-3,4-dihydro-2h-1,4-benzoxazine-7-sulfonamide (CAS 3656-85-7)
Recommended Standards
- 6-(Tert-butyl)-2-chloro-4-(trifluoromethyl)nicotinonitrile (CAS 914208-21-2)
- 2,2-difluoro-2H-1,3-benzodioxole-5-sulfonyl chloride (CAS 313681-67-3)
- 2-(4-Fluorobenzoyl)benzoyl chloride (CAS 58677-60-4)
- 6-Chloro-1-ethyl-2-methyl-5-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 1736-34-1)
- 3-Chloro-N-(prop-2-yn-1-yl)aniline (CAS 64798-32-9)
- N-(2-Phenylethyl)-4,5-dihydro-1,3-thiazol-2-amine (CAS 91215-17-7)
- 2,2'-(1-Methylpiperidine-4,4-diyl)bis(ethan-1-ol) (CAS 3187-33-5)
- Benzyl ((1-(2-hydroxyethyl)pyrrolidin-2-yl)methyl)carbamate (CAS 1353984-51-6)
- 3-Amino-N-(2-fluorobenzyl)benzamide (CAS 954577-03-8)
- 3-(Furan-2-yl)-6-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 954254-90-1)
- 1,1,1-Trifluoro-2-(4-methylpyridin-2-yl)propan-2-yl methanesulfonate (CAS 1396893-44-9)
- N-(4-(4-Methoxypiperidin-1-yl)phenyl)cyclohex-3-ene-1-carboxamide (CAS 1448033-57-5)
- methyl 2-(bromomethyl)oxazole-4-carboxylate (CAS 175551-77-6)
- Peptide 46 (H-4054.0500) (CAS 192122-40-0)
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