Tegoprazan Impurity 8 CAS 1270294-05-7
| CAS No. | 1270294-05-7 |
| Molecular Formula | C9H8F2O2 |
| Molecular Weight | 186.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tegoprazan Impurity 8 (C9H8F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Tegoprazan Impurity 8 (CAS 1270294-05-7) is a certified pharmaceutical impurity reference standard with the molecular formula C9H8F2O2 and a molecular weight of 186.16 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tegoprazan Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8F2O2 |
| Molecular Weight | 186.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Tegoprazan Standards
- Tegoprazan Impurity 56 (CAS 1341354-59-3)
- Tegoprazan Impurity 9 (CAS 942195-91-7)
- Tegoprazan Impurity 99 (CAS CATO-C4X-229799)
- Tegoprazan impurity 45 (CAS 1111086-20-4)
- Tegoprazan Impurity 11 (CAS CATO-C4X-229711)
- Tegoprazan Impurity 79 (CAS CATO-C4X-229779)
- Tegoprazan Impurity 65 (CAS CATO-C4X-229765)
- Tegoprazan Impurity 95 (CAS 2166713-42-2)
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- Upadacitinib Impurity 11 (CAS 1708997-43-6)
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