Lenvatinib Impurity 102 CAS 15568-85-1
| CAS No. | 15568-85-1 |
| Molecular Formula | C8H10O5 |
| Molecular Weight | 186.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Lenvatinib Impurity 102 (CAS 15568-85-1) is a certified pharmaceutical impurity reference standard with the molecular formula C8H10O5 and a molecular weight of 186.16 g/mol.
The molecular framework of Lenvatinib Impurity 102 (C8H10O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H10O5 |
| Molecular Weight | 186.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Lenvatinib Standards
- Lenvatinib Impurity 142 (CAS 1069122-99-1)
- Lenvatinib Impurity 99 (CAS 756488-67-2)
- Lenvatinib Impurity 175 (CAS CATO-C4X-1140175)
- Lenvatinib Impurity 70 (CAS 56962-03-9)
- Lenvatinib Impurity N1 (CAS 28443-57-4)
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