Sitafloxacin Impurity N14 CAS 127199-27-3
| CAS No. | 127199-27-3 |
| Molecular Formula | C13H7ClF3NO3 |
| Molecular Weight | 317.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Sitafloxacin Impurity N14 (CAS 127199-27-3), a pharmacopoeial impurity reference standard (molecular formula C13H7ClF3NO3, MW 317.65 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Sitafloxacin Impurity N14 (C13H7ClF3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 317.65 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Sitafloxacin Impurity N14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H7ClF3NO3 |
| Molecular Weight | 317.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Sitafloxacin Standards
- Sitafloxacin Impurity 34 (CAS 2365490-44-2)
- Sitafloxacin Impurity 35 (CAS CATO-C4X-115535)
- Sitafloxacin impurity 56 (CAS CATO-C4X-115556)
- Sitafloxacin impurity 55 (CAS CATO-C4X-115555)
- R-Sitafloxacin Impurity 47 (CAS 1432056-70-6)
- S-Sitafloxacin Impurity 48 (CAS 144282-37-1)
- Sitafloxacin impurity 59 (CAS 1542764-78-2)
- Sitafloxacin Impurity 37 (CAS CATO-C4X-115537)
Recommended Standards
- Trazodone impurity 40 (CAS 328410-01-1)
- Ethyl 7-chloro-6-(difluoromethoxy)-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 115700-25-9)
- Trazodone Impurity 107 (CAS CATO-C4X-1772107)
- 4-Methoxy-3-(2,2,2-trifluoroacetamido)benzenesulfonyl chloride (CAS 1184086-20-1)
- Atorvastatin Impurity 22 (CAS 1035205-25-4)
- Neostigmine Impurity 27 (CAS 63468-95-1)
- Daprodustat Impurity 40 (CAS CATO-C4X-240740)
- Chlorodimethyl(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-n-octyl)silane (CAS 102488-47-1)
- N-(5-(benzyloxy)-2,4-dichlorophenyl)-4-nitrobenzamide (CAS 338961-20-9)
- 2-(Aminomethyl)-4-methylphenol (CAS 65456-39-5)
- (R)-3-(2-Hydroxypropyl)-5-methoxy-2-methylcyclohexa-2,5-diene-1,4-dione (CAS 190895-96-6)
- 2-Bromo-n-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide (CAS 1424129-83-8)
- 3-(2,2-Dichlorovinyl)-N-(4-methoxyphenyl)-2,2-dimethylcyclopropane-1-carboxamide (CAS 297146-27-1)
- [His]1-Acetylated Semaglutide (CAS CATO-C4X-2226219)
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