4-Chloro-2-phenyl-1-(pyrrolidin-1-yl)butan-1-one CAS 1272758-21-0
| CAS No. | 1272758-21-0 |
| Molecular Formula | C14H18ClNO |
| Molecular Weight | 251.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-2-phenyl-1-(pyrrolidin-1-yl)butan-1-one (CAS 1272758-21-0) is a high-purity analytical reference standard with the molecular formula C14H18ClNO and a molecular weight of 251.75 g/mol.
The molecular framework of 4-Chloro-2-phenyl-1-(pyrrolidin-1-yl)butan-1-one (C14H18ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-2-phenyl-1-(pyrrolidin-1-yl)butan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H18ClNO |
| Molecular Weight | 251.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 6-Chloro-2-(methylthio)-N-phenylpyrimidin-4-amine (CAS 86626-97-3)
- 1-(4-Benzyl-piperidin-1-yl)-2-chloro-ethanone (CAS 158890-32-5)
- 5-[(4-Chlorophenyl)sulfanyl]-4-methylpyrimidin-2-amine (CAS 338417-76-8)
- 5-(3-Chlorophenyl)-4-(prop-2-en-1-yl)-4h-1,2,4-triazole-3-thiol (CAS 92286-36-7)
- N, N- Dimethylalanine (CAS 19701-89-4)
- (2E)-1,2-Bis(4-methoxyphenyl)-3-{[4-(trifluoromethyl)phenyl]amino}prop-2-en-1-one (CAS 692287-94-8)
- 1-Fluoro-2-(piperidin-4-yl)propan-2-ol hydrochloride (CAS 2608050-11-7)
- 2-[3,5-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 365564-05-2 ACN-044048 (CAS 365564-05-2)
- 7-Methoxybenzo[d]thiazole-2-thiol (CAS 908355-82-8)
- (7-cyanobenzo[b]thiophen-2-yl)boronic acid (CAS 1119899-37-4)
- 3-Amino-2-methylbutanoic acid (CAS 32723-74-3)
- 4-(pyridin-3-ylmethoxy)phenol (CAS 1094283-57-4)
- 7-Fluorobenzo[d]thiazol-2-amine (CAS 20358-08-1)
- Peptide Impurity 28 (CAS 1350456-64-2)
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