6-Chloro-2-(methylthio)-N-phenylpyrimidin-4-amine CAS 86626-97-3
| CAS No. | 86626-97-3 |
| Molecular Formula | C11H10ClN3S |
| Molecular Weight | 251.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Chloro-2-(methylthio)-N-phenylpyrimidin-4-amine (C11H10ClN3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 6-Chloro-2-(methylthio)-N-phenylpyrimidin-4-amine (CAS 86626-97-3), a certified reference material (molecular formula C11H10ClN3S, MW 251.74 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Chloro-2-(methylthio)-N-phenylpyrimidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10ClN3S |
| Molecular Weight | 251.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-4-(3,4-dihydroisoquinolin-2(1H)-yl)-1,2,5-thiadiazole (CAS 1156936-20-7)
- 2-Chloro-N-(3-(methylthio)phenyl)pyrimidin-4-amine (CAS 1248815-62-4)
- 2-(3-Chloro-phenyl)-2,6-dihydro-4h-thieno[3,4-c]pyrazol-3-ylamine (CAS 214542-51-5)
- 2-(4-Chloro-phenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-ylamine (CAS 214542-52-6)
- 4-Chloro-6-((methylthio)methyl)-2-(pyridin-4-yl)pyrimidine (CAS 478031-37-7)
- 4-Chloro-6-(p-tolylthio)pyrimidin-2-amine (CAS 339017-61-7)
- 2-chloro-N-cyclohexyl-N-phenylacetamide (CAS 100721-33-3)
- (5-Chloro-2-(methylamino)phenyl)(cyclohexyl)methanone (CAS 122908-18-3)
Recommended Standards
- 5-[(4-Chlorophenyl)sulfanyl]-4-methylpyrimidin-2-amine (CAS 338417-76-8)
- 5-(3-Chlorophenyl)-4-(prop-2-en-1-yl)-4h-1,2,4-triazole-3-thiol (CAS 92286-36-7)
- 7-Chloro-1,2,2,4-tetramethyl-1,2,3,4-tetrahydroquinoline-6-carbaldehyde (CAS 1243545-57-4)
- 4-Chloro-2-phenyl-1-(pyrrolidin-1-yl)butan-1-one (CAS 1272758-21-0)
- 3-Chloro-4-fluoro-4-(4-methylpiperazinomethyl) benzophenone (CAS 898783-85-2)
- 3-(Boc-amino)-4-[3-(trifluoromethyl)phenyl]butyric Acid (CAS 939802-49-0)
- (S)-2-Acetamido-4-mercaptobutanoic acid (CAS 7378-21-4)
- 4,4-Dimethoxydihydro-2H-pyran-3(4H)-one 693245-80-6 KS-000007OL (CAS 693245-80-6)
- Ethyl 5-bromo-3-fluoropicolinate (CAS 1214377-71-5)
- 3-Amino-N'-[(2E)-azepan-2-ylidene]benzohydrazide (CAS 1786065-39-1)
- 7-Chloro-1-methyl-1H-benzo[d]imidazole (CAS 4887-87-0)
- 1,3-Dimethyl-1-{3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl}urea (CAS 1000929-95-2)
- 1-Fluoro-2-iodo-3-methoxy-4-methylbenzene (CAS 2383375-38-8)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
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