1-(6-(Trifluoromethyl)pyridin-2-yl)piperazine CAS 127561-18-6
| CAS No. | 127561-18-6 |
| Molecular Formula | C10H12F3N3 |
| Molecular Weight | 231.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(6-(Trifluoromethyl)pyridin-2-yl)piperazine.
CATO supplies 1-(6-(Trifluoromethyl)pyridin-2-yl)piperazine (CAS 127561-18-6), a certified reference material (molecular formula C10H12F3N3, MW 231.22 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H12F3N3, 1-(6-(Trifluoromethyl)pyridin-2-yl)piperazine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 231.22 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(6-(Trifluoromethyl)pyridin-2-yl)piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12F3N3 |
| Molecular Weight | 231.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 3-(5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pentanenitrile (CAS 1171174-97-2)
- 1-(4-(Trifluoromethyl)pyridin-2-yl)piperazine (CAS 118708-88-6)
- 1-(5-(Trifluoromethyl)pyridin-2-yl)pyrrolidin-3-amine (CAS 1242850-54-9)
- 1-(6-(Trifluoromethyl)pyridin-2-yl)pyrrolidin-3-amine (CAS 1251125-95-7)
- 1-(5-(Trifluoromethyl)pyridin-2-yl)piperazine (CAS 132834-58-3)
- (S)-1-(5-(Trifluoromethyl)pyridin-2-yl)pyrrolidin-3-amine (CAS 202267-08-1)
- 1-(2-(Trifluoromethyl)pyridin-4-yl)piperazine (CAS 845617-32-5)
- 1-[3-(Trifluoromethyl)pyrid-2-yl]piperazine (CAS 87394-63-6)
Recommended Standards
- 3'-Amino-6-fluoro-[1,1'-biphenyl]-3-carboxylic acid (CAS 1261990-77-5)
- 4-(4-Fluorobenzoyl)-1-methyl-1H-pyrrole-2-carbaldehyde (CAS 128843-61-8)
- 6-(3-Fluoro-4-methylphenyl)nicotinic acid (CAS 1261989-30-3)
- 3-Amino-5-[4-(trifluoromethyl)phenyl]-1H-pyrazole (CAS 130599-34-7)
- (Z)-3,9-Dihydro-6H-purin-6-imine (CAS 134434-48-3)
- 2-amino-N-(5-bromo-2-methylphenyl)acetamide (CAS 1157171-39-5)
- 3,5-Dimethylthiazolo[5,4-c]isoxazole (CAS 221558-41-4)
- 1-[(2,4-Dichlorophenyl)methoxy]-2-(4-methoxyphenyl)-1H-imidazo[4,5-b]pyridine (CAS 339027-99-5)
- 4-Ethyl-1-naphthoic Acid (CAS 91902-58-8)
- n-(4-Methoxyphenyl)prop-2-enamide (CAS 7766-37-2)
- 2-((4-Nitrophenoxy)methyl)pyridine (CAS 145654-42-8)
- 2-Aminoethyl methanethiosulfonate hydrochloride (CAS 37597-96-9)
- N-(3-(5,7-Dimethylbenzo[d]oxazol-2-yl)-2-methylphenyl)-3-methoxybenzamide (CAS 590395-80-5)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
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