1-[3-(Trifluoromethyl)pyrid-2-yl]piperazine CAS 87394-63-6
| CAS No. | 87394-63-6 |
| Molecular Formula | C10H12F3N3 |
| Molecular Weight | 231.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-[3-(Trifluoromethyl)pyrid-2-yl]piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-[3-(Trifluoromethyl)pyrid-2-yl]piperazine (CAS 87394-63-6) is a high-purity analytical reference standard with the molecular formula C10H12F3N3 and a molecular weight of 231.22 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 1-[3-(Trifluoromethyl)pyrid-2-yl]piperazine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 231.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H12F3N3 |
| Molecular Weight | 231.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 3-(5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pentanenitrile (CAS 1171174-97-2)
- 1-(4-(Trifluoromethyl)pyridin-2-yl)piperazine (CAS 118708-88-6)
- 1-(5-(Trifluoromethyl)pyridin-2-yl)pyrrolidin-3-amine (CAS 1242850-54-9)
- 1-(6-(Trifluoromethyl)pyridin-2-yl)pyrrolidin-3-amine (CAS 1251125-95-7)
- 1-(6-(Trifluoromethyl)pyridin-2-yl)piperazine (CAS 127561-18-6)
- 1-(5-(Trifluoromethyl)pyridin-2-yl)piperazine (CAS 132834-58-3)
- (S)-1-(5-(Trifluoromethyl)pyridin-2-yl)pyrrolidin-3-amine (CAS 202267-08-1)
- 1-(2-(Trifluoromethyl)pyridin-4-yl)piperazine (CAS 845617-32-5)
Recommended Standards
- 1-[5-(Trifluoromethyl)-3-pyridinyl]-piperazine (CAS 872592-47-7)
- 2-(Piperidin-4-yl)-5-(trifluoromethyl)pyrimidine (CAS 944903-11-1)
- (E)-N-(2-fluorophenyl)-3-(furan-2-yl)acrylamide (CAS 853349-17-4)
- 2-[(3-Fluorophenyl)amino]benzoic acid (CAS 54-59-1)
- N1-Benzyl-N2-isopropylethane-1,2-diamine (CAS 57857-10-0)
- 4-Methyl-3-{1-methyl-3-phenyl-1H-thieno[2,3-c]pyrazol-5-yl}-5-(methylsulfanyl)-4H-1,2,4-triazole (CAS 478067-05-9)
- Methyl 5-(2-fluorobenzyl)-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate (CAS 477845-45-7)
- N-Boc-D-homoserine tert-Butyl Ester (CAS 110207-49-3)
- Dichlorisone (CAS 7008-26-6)
- (R)-1-(2-(aminomethyl)morpholino)ethan-1-one (CAS 1268520-08-6)
- 2,3,6-Trimethyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one (CAS 1956335-58-2)
- 1-(2-Carboxyethyl)-4-iodo-1H-pyrazole-3-carboxylic acid (CAS 1354706-73-2)
- 3-(naphthalen-2-yl)thiomorpholine (CAS 1344035-47-7)
- Acetyl Tetrapeptide-11 (CAS 928006-88-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com