Ethyl 5-chloro-3-methyl-1-benzothiophene-2-carboxylate CAS 127606-11-5
| CAS No. | 127606-11-5 |
| Molecular Formula | C12H11ClO2S |
| Molecular Weight | 254.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 5-chloro-3-methyl-1-benzothiophene-2-carboxylate is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ethyl 5-chloro-3-methyl-1-benzothiophene-2-carboxylate (CAS 127606-11-5), a certified reference material (molecular formula C12H11ClO2S, MW 254.73 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Ethyl 5-chloro-3-methyl-1-benzothiophene-2-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 254.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 5-chloro-3-methyl-1-benzothiophene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11ClO2S |
| Molecular Weight | 254.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- 2-chloro-N-(1-methanesulfonylpiperidin-4-yl)acetamide (CAS 1157073-39-6)
- (2-Chloro-4-fluorophenyl)(cycloheptyl)methanone (CAS 1443302-83-7)
- 2-(3-Chloro-5-fluorophenyl)-ethyl cyclopentyl ketone (CAS 898751-70-7)
- 3-chloro-6-(propan-2-yl)-1-benzothiophene-2-carboxylic acid (CAS 923759-70-0)
- 2-chloro-1-[4-(pyrimidin-2-yl)piperazin-1-yl]propan-1-one (CAS 1016805-23-4)
- 2-Chloro-N-(1-pyrazin-2-yl-piperidin-3-yl)-acetamide (CAS 1065484-53-8)
- 5-Chloro-N-(2-(pyrrolidin-1-yl)ethyl)pyrazine-2-carboxamide (CAS 1160264-34-5)
- 2-Chloro-1-(4-(pyrazin-2-yl)piperazin-1-yl)propan-1-one (CAS 1178055-92-9)
Recommended Standards
- 1-(Naphthalen-1-yl)ethane-1-sulfonyl chloride (CAS 1249583-73-0)
- 2-((4-Fluorophenyl)thio)ethane-1-sulfonyl chloride (CAS 1354949-84-0)
- 2-(Naphthalen-1-yl)ethanesulfonyl chloride (CAS 104296-63-1)
- 2-methoxy-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-3-sulfonyl chloride (CAS 1799541-49-3)
- 2-Cyano-n-(2,4-dichlorophenyl)-2-(4-oxo-3-phenyl-1,3-thiazolidin-2-ylidene)acetamide (CAS 924872-99-1)
- (2Z)-2-[(Pyridin-2-yl)methylidene]-1-azabicyclo[2.2.2]octan-3-one (CAS 410087-17-1)
- 2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-6-methoxychroman-4-one (CAS 136498-37-8)
- 4-(Piperazin-1-yl)-1H-pyrrolo[2,3-d]pyrimidine (CAS 252722-52-4)
- N-[(1R,2R)-2-(Dimethylamino)cyclohexyl]-N'-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thiourea (CAS 933456-78-1)
- 2-(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)-6-ethoxybenzo[d]thiazole (CAS 863000-99-1)
- 1-(trideuteriomethyl)cyclopropanol (CAS 60153-90-4)
- N-[(Pyridin-3-yl)methyl]-2-[2-(trifluoromethyl)-1H-1,3-benzodiazol-1-yl]propanamide (CAS 478080-06-7)
- 2-Chloro-5-methoxybenzamide (CAS 62798-01-0)
- Fibrinopeptide B (human) (CAS 36204-23-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com