N-[(Pyridin-3-yl)methyl]-2-[2-(trifluoromethyl)-1H-1,3-benzodiazol-1-yl]propanamide CAS 478080-06-7
| CAS No. | 478080-06-7 |
| Molecular Formula | C17H15F3N4O |
| Molecular Weight | 348.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-[(Pyridin-3-yl)methyl]-2-[2-(trifluoromethyl)-1H-1,3-benzodiazol-1-yl]propanamide (CAS 478080-06-7), molecular formula C17H15F3N4O and molecular weight 348.32 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-[(Pyridin-3-yl)methyl]-2-[2-(trifluoromethyl)-1H-1,3-benzodiazol-1-yl]propanamide (C17H15F3N4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H15F3N4O |
| Molecular Weight | 348.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- N-(pyridin-4-ylmethyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide (CAS 439111-84-9)
- 5-(Pyridin-4-yl)-1-(3-(trifluoromethyl)benzyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1338654-77-5)
- N-(2-(3-(Pyridin-4-yl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)ethyl)propane-1-sulfonamide (CAS 1797715-58-2)
- 1-(Pyridin-4-yl)-N-(p-tolyl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carbothioamide (CAS 393832-49-0)
- (1-Benzyl-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)(piperidin-1-yl)methanone (CAS 1798524-72-7)
- N-[(Pyridin-2-yl)methyl]-4,6-bis(trifluoromethyl)pyridine-2-carboxamide (CAS 1092345-09-9)
- N-(pyridin-3-ylmethyl)-4,6-bis(trifluoromethyl)picolinamide (CAS 1092345-12-4)
- 2-(Pyridin-3-yl)-N-(3-(trifluoromethyl)phenyl)thiazole-4-carboxamide (CAS 338397-00-5)
Recommended Standards
- 1-(4-fluorophenyl)-3-methyl-6-pyridin-3-yl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011396-91-0)
- N-(5-fluoro-2-methylphenyl)-2-((4-methyl-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 303091-07-8)
- Methyl 6-(4-fluorophenyl)-3-phenylisoxazolo[5,4-b]pyridine-4-carboxylate (CAS 1018125-83-1)
- 7-Hydroxy-2-isopropyl-3-(4-(trifluoromethyl)phenyl)quinazolin-4(3H)-one (CAS 871814-07-2)
- 4-Ethoxy-1H-pyrazole (CAS 81437-10-7)
- Clascoterone D6 (CAS CATO-C4X-33315)
- N1-(5-methylisoxazol-3-yl)oxalamide (CAS 668462-73-5)
- (E)-4-((4-methoxyphenyl)diazenyl)benzene-1,3-diamine hydrochloride (CAS 68936-13-0)
- 5-(hydrazinecarbonyl)-N,2,4-trimethyl-1H-pyrrole-3-carboxamide (CAS 1803588-39-7)
- 2-(2,5-Dimethylphenoxy)acetohydrazide (CAS 103896-91-9)
- 4-Methoxy-3-ureidobenzoic acid (CAS 861792-86-1)
- 3,4-Dihydro-7-hydroxyquinoline-2(1H)-one-d (CAS 1215336-37-0)
- 2-(3,4-Dichlorophenyl)-6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 477858-75-6)
- Des-Trp25-Tirzepatide (CAS CATO-CPTD788948)
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