methyl 3-(5-chloro-2-methoxyphenyl)-1H-pyrazole-5-carboxylate CAS 1276540-40-9
| CAS No. | 1276540-40-9 |
| Molecular Formula | C12H11ClN2O3 |
| Molecular Weight | 266.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
methyl 3-(5-chloro-2-methoxyphenyl)-1H-pyrazole-5-carboxylate (CAS 1276540-40-9), molecular formula C12H11ClN2O3 and molecular weight 266.68 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of methyl 3-(5-chloro-2-methoxyphenyl)-1H-pyrazole-5-carboxylate (C12H11ClN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11ClN2O3 |
| Molecular Weight | 266.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related methyl Standards
- 1-((4-Chloro-2-methylphenoxy)methyl)-1h-pyrazole-3-carboxylic acid (CAS 1004193-09-2)
- 1-(2-Chloro-5-methylphenoxymethyl)-1h-pyrazole-3-carboxylic acid (CAS 1004193-11-6)
- 4-chloro-1-[(4-methylphenoxy)methyl]-1H-pyrazole-3-carboxylic acid (CAS 1006444-40-1)
- Methyl 5-chloro-6-cyclopropyl-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate (CAS 1011398-90-5)
- 1015844-55-9 [1-(3-Chloro-phenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-acetic acid (CAS 1015844-55-9)
- 2-Chloro-3-((4-nitrophenyl)amino)cyclohex-2-en-1-one (CAS 1022597-48-3)
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- Ethyl 4-chloro-7-methoxyquinazoline-2-carboxylate (CAS 1189107-22-9)
Recommended Standards
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- 2-Chloro-N-(4-(4-methoxyphenyl)isoxazol-5-yl)acetamide (CAS 1232776-82-7)
- 1-(4-Chlorophenyl)-N-methyl-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1300712-92-8)
- 3-Bromo-8-chloroquinolin-2-amine (CAS 1447960-43-1)
- Ethanamine, 2-[(3,4-dimethylphenyl)thio]- (CAS 192634-83-6)
- 2-(4-Fluorophenyl)-2-phenylaceticacid (CAS 723-69-3)
- S-(2-chloro-6-fluorobenzyl)-L-cysteine (CAS 1241383-43-6)
- 2-(2-Fluorobenzylidene)malononitrile (CAS 2698-43-3)
- Ilaprazole Dimer Impurity 51 (CAS 1114985-75-9)
- Peramivir Impurity 103 (CAS CATO-C4X-1833103)
- 2-phenyl-2,8-diazaspiro[4.5]decan-3-one hydrochloride (CAS 1047657-67-9)
- Methyl (2Z)-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-2-(4-methylbenzenesulfonyl)prop-2-enoate (CAS 1327196-04-2)
- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
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