5,7-Dichloro-4-hydroxyquinoline-3-carbohydrazide CAS 127720-05-2
| CAS No. | 127720-05-2 |
| Molecular Formula | C10H7Cl2N3O2 |
| Molecular Weight | 272.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 272.09 g/mol gives 5,7-Dichloro-4-hydroxyquinoline-3-carbohydrazide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5,7-Dichloro-4-hydroxyquinoline-3-carbohydrazide (CAS 127720-05-2) is a high-purity analytical reference standard with the molecular formula C10H7Cl2N3O2 and a molecular weight of 272.09 g/mol.
5,7-Dichloro-4-hydroxyquinoline-3-carbohydrazide (C10H7Cl2N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5,7-Dichloro-4-hydroxyquinoline-3-carbohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7Cl2N3O2 |
| Molecular Weight | 272.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloro Standards
- 4,5-Dichloro-1-(4-nitrobenzyl)-1H-imidazole (CAS 1081145-80-3)
- 2-(3,4-Dichloro-5-methylphenyl)-1,2,4-triazine-3,5(2H,4H)-dione (CAS 38613-10-4)
- 2-(6,8-Dichloro-4-oxoquinazolin-3(4H)-yl)acetamide (CAS 98994-14-0)
- 6,7-Dichloro-3,5-dihydro-1-hydroxyimidazo[1,2-α]quinazolin-2(1H)-one(Anagrelide Impurity) (CAS 875467-41-7)
- Methyl 6,8-dichloro-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 1065074-55-6)
- Methyl 5,7-dichloro-4-hydroxyquinoline-2-carboxylate (CAS 130613-19-3)
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- 3,4-Dichloro-1-(2-methoxyphenyl)-1H-pyrrole-2,5-dione (CAS 29236-13-3)
Recommended Standards
- 3-Iodo-1,6-dimethyl-1H-indazole (CAS 1257535-50-4)
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- 1-[(2,4-dichlorophenyl)methyl]-1H-1,2,3-triazole-4-carboxylic acid (CAS 1253906-28-3)
- 5-Chloro-1-(2-chlorobenzyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1355217-13-8)
- 2-(chloromethyl)prop-2-enenitrile (CAS 7659-44-1)
- N-((3-(trifluoromethyl)benzoyl)oxy)-1,2,3-thiadiazole-4-carboxamide (CAS 341965-58-0)
- 2,2,2-Trifluoroethyl n-(4-methyl-3-nitrophenyl)carbamate (CAS 1087798-32-0)
- 5-(3-(Dimethoxymethyl)phenyl)furan-2-carbaldehyde (CAS 886509-67-7)
- 3-(3-(4-Nitrophenyl)acrylamido)benzene-1-sulfonyl fluoride (CAS 19160-19-1)
- 2-(4-Methoxyphenyl)-2-oxoacetaldehyde (CAS 1076-95-5)
- 4-Methyl-5-(propylsulfanyl)-1,2,3-thiadiazole (CAS 338420-74-9)
- 3-(Pyridin-3-yl)phenol (CAS 93851-31-1)
- 2-Methylfuro[2,3-b]pyridine (CAS 75332-26-2)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
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