6,7-Dichloro-3,5-dihydro-1-hydroxyimidazo[1,2-α]quinazolin-2(1H)-one(Anagrelide Impurity) CAS 875467-41-7
| CAS No. | 875467-41-7 |
| Molecular Formula | C10H7Cl2N3O2 |
| Molecular Weight | 272.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6,7-Dichloro-3,5-dihydro-1-hydroxyimidazo[1,2-α]quinazolin-2(1H)-one(Anagrelide Impurity) (C10H7Cl2N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
6,7-Dichloro-3,5-dihydro-1-hydroxyimidazo[1,2-α]quinazolin-2(1H)-one(Anagrelide Impurity) (CAS 875467-41-7) is a high-purity analytical reference standard with the molecular formula C10H7Cl2N3O2 and a molecular weight of 272.09 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6,7-Dichloro-3,5-dihydro-1-hydroxyimidazo[1,2-α]quinazolin-2(1H)-one(Anagrelide Impurity) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7Cl2N3O2 |
| Molecular Weight | 272.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloro Standards
- 4,5-Dichloro-1-(4-nitrobenzyl)-1H-imidazole (CAS 1081145-80-3)
- 5,7-Dichloro-4-hydroxyquinoline-3-carbohydrazide (CAS 127720-05-2)
- 2-(3,4-Dichloro-5-methylphenyl)-1,2,4-triazine-3,5(2H,4H)-dione (CAS 38613-10-4)
- 2-(6,8-Dichloro-4-oxoquinazolin-3(4H)-yl)acetamide (CAS 98994-14-0)
- Methyl 6,8-dichloro-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 1065074-55-6)
- Methyl 5,7-dichloro-4-hydroxyquinoline-2-carboxylate (CAS 130613-19-3)
- Methyl 5,7-dichloro-4-hydroxyquinoline-3-carboxylate (CAS 1820685-13-9)
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Recommended Standards
- 6-((3,4-Dichlorophenyl)amino)pyrimidine-2,4(1H,3H)-dione (CAS 6972-74-3)
- methyl 2-(2-bromo-3-pyridyl)-2,2-difluoro-acetate (CAS 2761389-76-6)
- 4-Iodo-5,6-dimethyl-1H-benzo[d]imidazole (CAS 2411789-56-3)
- Lamotrigine Impurity 11 (CAS CATO-C4X-167211)
- 1-Ethyl-3-(2,4-difluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 1369018-01-8)
- 1-(1-Propyl-1H-1,2,3-triazol-4-yl)ethan-1-one (CAS 1849227-01-5)
- 1-(4-Nitrophenyl)-5-phenyl-1H-pyrazole (CAS 62160-33-2)
- N-(3,4-difluorophenyl)-N-methylglycine (CAS 1218669-49-8)
- (R)-2-((3aS,4S,6S,7aR)-5,5-dimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)pyrrolidine hydrochloride (CAS 1056211-24-5)
- 1-(4-Methoxyphenyl)-5-(1h-pyrrol-1-yl)-1h-pyrazole-4-carboxylic acid (CAS 116834-10-7)
- 4-Fluoro-7-methyl-2-(pyridin-3-yl)indoline (CAS 595545-07-6)
- 9H,9'H-[9,9'-Bifluoren]-9-ol (CAS 981-46-4)
- 2-Fluoro-1,3,5-trimethylbenzene (CAS 392-69-8)
- Tirzepatide Impurity 25 X TFA Salt (CAS CATO-C4X-324025)
Why CATO?
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