Bromfenac Impurity 30 CAS 1279501-08-4
| CAS No. | 1279501-08-4 |
| Molecular Formula | C15H9Br2NO |
| Molecular Weight | 379.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Bromfenac Impurity 30 (CAS 1279501-08-4, C15H9Br2NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C15H9Br2NO, Bromfenac Impurity 30 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 379.05 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Bromfenac Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H9Br2NO |
| Molecular Weight | 379.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromfenac Standards
- Bromfenac Impurity 49 (CAS 91714-66-8)
- Bromfenac Impurity 14 (CAS CATO-C4X-200214)
- Bromfenac Impurity 54 (CAS CATO-C4X-200254)
- Bromfenac Impurity 35 (CAS CATO-C4X-200235)
- Bromfenac Impurity 34 (CAS CATO-C4X-200234)
- Bromfenac Impurity 18 (CAS CATO-C4X-200218)
- Bromfenac Impurity 75 (CAS 91715-34-3)
- Bromfenac Impurity 43 (CAS CATO-C4X-200243)
Recommended Standards
- Carbamazepine Impurity 39 (CAS 53003-61-5)
- 5-(3-Bromophenyl)-3-(4-bromophenyl)isoxazole (CAS 651021-66-8)
- 2-[(2-Bromo-4-nitrophenyl)sulfanyl]-1,3-dichlorobenzene (CAS 477888-99-6)
- 4-bromo-3-(bromomethyl)-7-(trifluoromethyl)isoquinoline (CAS 2195350-07-1)
- Pazopanib Impurity 63 (CAS 2369664-23-1)
- Gimeracil Impurity 1 (CAS CATO-C4X-12141)
- S-Sitafloxacin Impurity 48 (CAS 144282-37-1)
- 3-(1-Methylpiperidin-4-yl)propanoic acid hydrochloride (CAS 103039-94-7)
- 2-(Propan-2-yl)benzene-1-sulfonyl chloride (CAS 61738-47-4)
- 2-Amino-4,5-dimethyl-1-(2,4,6-tribromophenyl)-1H-pyrrole-3-carbonitrile (CAS 291539-77-0)
- 1-Methyl-2-(piperidin-4-yloxy)-1H-benzo[d]imidazole hydrochloride (CAS 1185311-04-9)
- 1-Phenyl-2-(9H-thioxanthen-9-ylidene)ethan-1-one (CAS 178753-74-7)
- 2-(Cyanomethyl)-5,6-difluorobenzimidazole (CAS 898045-14-2)
- Peptide 436 (CAS CATO-CPTD788436)
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