Bromfenac Impurity 49 CAS 91714-66-8
| CAS No. | 91714-66-8 |
| Molecular Formula | C15H9Br2NO |
| Molecular Weight | 379.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Bromfenac Impurity 49 (CAS 91714-66-8, C15H9Br2NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Bromfenac Impurity 49 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 379.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Bromfenac Impurity 49 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H9Br2NO |
| Molecular Weight | 379.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromfenac Standards
- Bromfenac Impurity 30 (CAS 1279501-08-4)
- Bromfenac Impurity 14 (CAS CATO-C4X-200214)
- Bromfenac Impurity 54 (CAS CATO-C4X-200254)
- Bromfenac Impurity 35 (CAS CATO-C4X-200235)
- Bromfenac Impurity 34 (CAS CATO-C4X-200234)
- Bromfenac Impurity 18 (CAS CATO-C4X-200218)
- Bromfenac Impurity 75 (CAS 91715-34-3)
- Bromfenac Impurity 43 (CAS CATO-C4X-200243)
Recommended Standards
- 2-[(2-Bromo-4-nitrophenyl)sulfanyl]-1,3-dichlorobenzene (CAS 477888-99-6)
- Carbamazepine Impurity 39 (CAS 53003-61-5)
- 2-(Difluoromethyl)-3-iodo-5-nitropyridine-6-sulfonamide (CAS 1805195-55-4)
- 5-(3-Bromophenyl)-3-(4-bromophenyl)isoxazole (CAS 651021-66-8)
- Silodosin impurity 25 HCl (CAS CATO-C4X-175425)
- Oxybutynin Impurity 19 (CAS CATO-C4X-197219)
- Baloxavir Marboxil Impurity 204 (CAS CATO-C4X-2108204)
- 5-(Hydroxymethyl)-1-methylpyrrolidin-3-ol (CAS 1822519-38-9)
- rel-Benthiavalicarb (CAS 413615-35-7)
- Methyl (2Z)-3-[(3,4-dimethoxyphenyl)amino]-2-(4-methylbenzenesulfonyl)prop-2-enoate (CAS 1327176-86-2)
- 5-Chloro-2-(difluoromethyl)aniline (CAS 1261672-89-2)
- 5-Ethyl-N-((4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)methyl)thiophene-2-sulfonamide (CAS 1203111-98-1)
- 4,6-Dihydroxy-5-methylisophthalaldehyde (CAS 22304-67-2)
- D-Tyr10-Tirzepatide (CAS CATO-CPTD788922)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com