5-(Trifluoromethyl)pyridine-2-carbonyl chloride CAS 128073-05-2
| CAS No. | 128073-05-2 |
| Molecular Formula | C7H9ClF3NO |
| Molecular Weight | 215.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(Trifluoromethyl)pyridine-2-carbonyl chloride is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-(Trifluoromethyl)pyridine-2-carbonyl chloride (CAS 128073-05-2), molecular formula C7H9ClF3NO and molecular weight 215.60 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-(Trifluoromethyl)pyridine-2-carbonyl chloride (C7H9ClF3NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 215.60 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H9ClF3NO |
| Molecular Weight | 215.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 2-(trifluoromethyl)pyridine-4-carbonyl chloride (CAS 1019201-53-6)
- 5-(trifluoromethyl)pyridine-3-carbonyl chloride (CAS 1092506-65-4)
- 4-(Trifluoromethyl)piperidine-1-carbonyl chloride (CAS 862274-38-2)
- 4-(trifluoromethyl)pyridine-2-carbonyl chloride (CAS 640296-12-4)
- 2-(Trifluoromethyl)-1,3-thiazole-4-carbonyl chloride (CAS 1076197-53-9)
- 5-(trifluoromethyl)-1,3-thiazole-4-carbonyl chloride (CAS 1245523-21-0)
- (4-(Trifluoromethyl)styryl)boronic acid (CAS 851660-03-2)
- (E)-(3-(Trifluoromethyl)styryl)boronic acid (CAS 698998-84-4)
Recommended Standards
- 2-chloro-6-(trifluoromethyl)pyridine-3-carbaldehyde (CAS 944900-06-5)
- 4-Nitrobenzyl Carbonochloridate (CAS 4457-32-3)
- Nintedanib Impurity 37 (CAS 14719-83-6)
- (E)-3-(6-Amino-3-chloro-2-fluorophenyl)acrylic acid (CAS 1094106-62-3)
- 1,3-Dibromo-2-iodo-5-(trifluoromethoxy)benzene (CAS 1000578-22-2)
- 8-Fluoro-2-methyl-1H,2H,3H,4H-benzo[b]1,6-naphthyridine-10-carboxylic acid (CAS 1016501-46-4)
- 3,3'-(1,4-phenylenebis(azanediyl))bis(5,5-dimethylcyclohex-2-enone) (CAS 78431-57-9)
- 2-(2-Chloro-4-((methylsulfonyl)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1338326-90-1)
- 5-Hydroxy Leflunomide-d4 (Metabolite M2) (CAS 1794789-76-6)
- 2-Fluoro-6-(trifluoromethyl)isonicotinaldehyde (CAS 1227565-35-6)
- 2-[1,1-Bis[(4S)-4,5-dihydro-4-phenyl-2-oxazolyl]ethyl]-4,5-dihydro-4,4-dimethyloxazole (CAS 1008748-76-2)
- N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-Pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride (CAS 1260590-51-9)
- N'-(4-Isopropylbenzyl)benzohydrazide (CAS 537672-69-8)
- Biotinyl-CBP501 Affinity Peptide trifluoroacetate salt (CAS 2022956-39-2)
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