Methyl 4-{[2-amino-4-(trifluoromethyl)phenyl]amino}benzoate CAS 1281348-84-2
| CAS No. | 1281348-84-2 |
| Molecular Formula | C15H13F3N2O2 |
| Molecular Weight | 310.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 310.27 g/mol gives Methyl 4-{[2-amino-4-(trifluoromethyl)phenyl]amino}benzoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 4-{[2-amino-4-(trifluoromethyl)phenyl]amino}benzoate (CAS 1281348-84-2) is a high-purity analytical reference standard with the molecular formula C15H13F3N2O2 and a molecular weight of 310.27 g/mol.
Based on its molecular formula C15H13F3N2O2, Methyl 4-{[2-amino-4-(trifluoromethyl)phenyl]amino}benzoate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 310.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 4-{[2-amino-4-(trifluoromethyl)phenyl]amino}benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H13F3N2O2 |
| Molecular Weight | 310.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 4-(2-Dimethylamino-5-trifluoromethyl-pyridin-3-yl)-benzoic acid (CAS 1311278-85-9)
- S-(1H-Benzo[d]imidazol-2-yl)-N-ethylthiohydroxylamine (CAS 149679-62-9)
- 2-[(2-hydroxyphenyl)sulfanyl]acetic acid (CAS 785793-89-7)
- 4-{[(2,2,2-Trifluoroacetyl)amino]methyl}benzenesulfonyl chloride (CAS 1183313-28-1)
- (6,7-Dihydro-5H-pyrrolo[1,2-b][1,2,4]triazol-5-yl)methanol (CAS 1369805-07-1)
- N,N-Dimethyl-4-(5-phenyloxazol-2-yl)aniline (CAS 10004-71-4)
- Ethyl 6-bromo-4-methoxynicotinate (CAS 1807226-98-7)
- 2-(3-Fluoro-2-(difluoromethoxy)benzoyl)pyridine (CAS 1261870-41-0)
- Trimethyl 3,3',3''-phosphinetriyltripropanoate (CAS 29269-17-8)
- 2,4-Dichloro-5-nitro-6-(trifluoromethyl)pyrimidine (CAS 715-42-4)
- Gastric Inhibitory Polypeptide (3-42) (human) trifluoroacetate salt (CAS 1802086-25-4)
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