1-Chloro-8-trifluoromethyl-isoquinoline CAS 1283719-92-5
| CAS No. | 1283719-92-5 |
| Molecular Formula | C10H5ClF3N |
| Molecular Weight | 231.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Chloro-8-trifluoromethyl-isoquinoline (CAS 1283719-92-5), molecular formula C10H5ClF3N and molecular weight 231.60 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 1-Chloro-8-trifluoromethyl-isoquinoline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 231.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Chloro-8-trifluoromethyl-isoquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H5ClF3N |
| Molecular Weight | 231.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-7-(trifluoromethyl)quinoline (CAS 104612-21-7)
- 6-Chloro-8-(trifluoromethyl)quinoline (CAS 1065074-68-1)
- 1-chloro-6-(trifluoromethyl)isoquinoline (CAS 1196152-92-7)
- 1-Chloro-7-(trifluoromethyl)isoquinoline (CAS 1196154-02-5)
- 4-Chloro-3-nitrotrifluorotoluene (CAS 121-17-5)
- 8-Chloro-6-(trifluoromethyl)quinoline (CAS 1215206-39-5)
- 3-Chloro-6-(trifluoromethyl)isoquinoline (CAS 1357945-78-8)
- 7-Chloro-6-(trifluoromethyl)quinoline (CAS 1375604-48-0)
Recommended Standards
- 6-Chloro-7-(trifluoromethyl)quinoline (CAS 152167-87-8)
- 4-Chloro-2-(trifluoromethyl)quinoline (CAS 1701-24-2)
- 7-Chloro-2-(trifluoromethyl)quinoline (CAS 176722-70-6)
- 8-Chloro-2-(trifluoromethyl)quinoline (CAS 1823887-29-1)
- 2-Chloro-3-iodobenzophenone (CAS 890098-15-4)
- 1-(5-(Chloromethyl)benzo[d]oxazol-2-yl)ethanone (CAS 1803836-51-2)
- 1-(2-furanylmethyl)piperazine dihydrochloride 1-(furan-2-ylmethyl)piperazine dihydrochloride 59037-70-6 A832125 (CAS 59037-70-6)
- 6-Amino-3,4-dihydroquinolin-2(1H)-one (CAS 22246-13-5)
- 2-(4-(Thiophene-3-carbonyl)morpholin-2-yl)acetic acid (CAS 1501249-44-0)
- 6-Chloro-3-iodo-4-methyl-1-trityl-1H-pyrazolo[4,3-c]pyridine (CAS 1589540-65-7)
- 4-Methoxy-3-(4-methyl-2,5-dioxoimidazolidin-4-yl)benzene-1-sulfonyl chloride (CAS 1052558-93-6)
- 1-(Pyrazin-2-yl)azetidin-3-amine dihydrochloride (CAS 1389313-56-7)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)benzonitrile (CAS 95711-33-4)
- Tau Peptide (273-284) trifluoroacetate salt (CAS 1663490-91-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com