4-Chloro-2-(trifluoromethyl)quinoline CAS 1701-24-2
| CAS No. | 1701-24-2 |
| Molecular Formula | C10H5ClF3N |
| Molecular Weight | 231.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-2-(trifluoromethyl)quinoline (C10H5ClF3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-Chloro-2-(trifluoromethyl)quinoline (CAS 1701-24-2) is a high-purity analytical reference standard with the molecular formula C10H5ClF3N and a molecular weight of 231.60 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-2-(trifluoromethyl)quinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H5ClF3N |
| Molecular Weight | 231.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-7-(trifluoromethyl)quinoline (CAS 104612-21-7)
- 6-Chloro-8-(trifluoromethyl)quinoline (CAS 1065074-68-1)
- 1-chloro-6-(trifluoromethyl)isoquinoline (CAS 1196152-92-7)
- 1-Chloro-7-(trifluoromethyl)isoquinoline (CAS 1196154-02-5)
- 4-Chloro-3-nitrotrifluorotoluene (CAS 121-17-5)
- 8-Chloro-6-(trifluoromethyl)quinoline (CAS 1215206-39-5)
- 1-Chloro-8-trifluoromethyl-isoquinoline (CAS 1283719-92-5)
- 3-Chloro-6-(trifluoromethyl)isoquinoline (CAS 1357945-78-8)
Recommended Standards
- 6-Chloro-7-(trifluoromethyl)quinoline (CAS 152167-87-8)
- 7-Chloro-2-(trifluoromethyl)quinoline (CAS 176722-70-6)
- 7-Chloro-6-(trifluoromethyl)quinoline (CAS 1375604-48-0)
- 8-Chloro-2-(trifluoromethyl)quinoline (CAS 1823887-29-1)
- 1-(tert-Butyl)-3-chloro-2-cyclopropoxybenzene (CAS 1243408-56-1)
- 3-(1-Methyl-1H-imidazol-2-yl)-2,4,5,5a,6,7,8,8a-octahydro-pyrrolo[3,4-g]indazole trihydrochloride (CAS 1361113-77-0)
- Tert-butyl 4-(2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-1-carboxylate (CAS 87120-81-8)
- (1S,3s)-3-((tert-butoxycarbonyl)amino)-1-methylcyclobutane-1-carboxylic acid (CAS 2231665-99-7)
- 5-Isothiocyanato-2-methoxy-4,6-dimethyl-pyrimidine (CAS 1173984-11-6)
- Dacomitinib Impurity 8 (CAS CATO-C4X-20868)
- Sodium 5-methyl-5-((R)-4-methylcyclohex-3-en-1-yl)-4,5-dihydroisoxazole-3-carboxylate (CAS 1217523-31-3)
- 2-Ethoxy-5-fluorobenzenesulfonyl chloride (CAS 67475-57-4)
- 7-Benzyl-2-(trifluoromethyl)-5,6,7,8-tetrahydro-1,7-naphthyridine (CAS 1356109-39-1)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
Why CATO?
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