2-Bromo-4-Chloro-1-(2,5-Difluorophenyl)Butan-1-One CAS 1284437-05-3
| CAS No. | 1284437-05-3 |
| Molecular Formula | C10H8BrClF2O |
| Molecular Weight | 297.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Bromo-4-Chloro-1-(2,5-Difluorophenyl)Butan-1-One (CAS 1284437-05-3) is a high-purity analytical reference standard with the molecular formula C10H8BrClF2O and a molecular weight of 297.52 g/mol.
The molecular framework of 2-Bromo-4-Chloro-1-(2,5-Difluorophenyl)Butan-1-One (C10H8BrClF2O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-Bromo-4-Chloro-1-(2,5-Difluorophenyl)Butan-1-One meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8BrClF2O |
| Molecular Weight | 297.52 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- (5-Bromo-2-chloropyrimidin-4-yl)(phenyl)methanone (CAS 1139634-98-2)
- 2-((5-Bromo-7-chloroquinolin-8-yl)oxy)acetonitrile (CAS 88757-52-2)
- 2-((7-Bromo-5-chloroquinolin-8-yl)oxy)acetonitrile (CAS 88757-16-8)
- 7-Bromo-4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile (CAS 2648419-66-1)
- 8-Bromo-2-chloro-7-methoxyquinoline-3-carbonitrile (CAS 948291-24-5)
- 2-((6-Bromo-3-chloro-5-nitropyrazin-2-yl)amino)ethanol (CAS 89407-82-9)
- 5-Bromo-2,3-dihydro-1-benzofuran-7-sulfonyl chloride (CAS 690632-00-9)
- (4-BROMO-2,5-DIFLUOROPHENYL)CHLOROSULFONE 207974-14-9 4-BROMO-2,5-DIFLUOROBENZENE-1-SULFONYL CHLORIDE 4-BROMO-2,5-DIFLUOROBENZENESULFONYL CHLORIDE 4-BROMO-2,5-DIFLUOROBENZENESULPHONYL CHLORIDE BC002879 BUTTPARK 23\07-77 (CAS 207974-14-9)
Recommended Standards
- (R)-2-[(Diethylamino)methyl]-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-cyclopenten-1-one (CAS 117254-07-6)
- 1-(3-Chloro-5-(methoxycarbonyl)phenyl)-4-methyl-2,6,7-trioxa-1-borabicyclo[2.2.2]octan-1-uide (CAS 1335281-55-4)
- 5-chloro-3-iodo-1-(²H₃)methyl-1H-pyrazolo[4,3-d]pyrimidine (CAS 2564785-56-2)
- 2-Chloro-6-iodo-3-isopropoxypyridine (CAS 1392467-05-8)
- 8-(2-Iodophenyl)-8-oxooctanenitrile (CAS 898768-09-7)
- 4-(Propylamino)butan-2-one (CAS 44857-32-1)
- Asulam sodium (CAS 2302-17-2)
- 1-Methyl-2-(3-piperidinyl)-1H-benzimidazole dihydrochloride (CAS 1263283-11-9)
- 3,6-Bis(5-bromothiophen-2-yl)-2,5-dihexylpyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione (CAS 1214906-01-0)
- 1-[(3-chlorophenyl)methyl]cyclopentane-1-carboxylic acid (CAS 1226034-44-1)
- 3-Methoxy-2-(methoxymethoxy)benzoic acid (CAS 1467210-82-7)
- Methyl 4,4-dimethylcyclohexanecarboxylate (CAS 828271-17-6)
- 2-(Difluoromethoxy)-6-propionylbenzonitrile (CAS 1806641-08-6)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com