2-((5-Bromo-7-chloroquinolin-8-yl)oxy)acetonitrile CAS 88757-52-2

Purity 97%+In StockPharmaceutical Standards
CAS No.88757-52-2
Molecular FormulaC11H6BrClN2O
Molecular Weight297.54 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-((5-Bromo-7-chloroquinolin-8-yl)oxy)acetonitrile CAS 88757-52-2 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-((5-Bromo-7-chloroquinolin-8-yl)oxy)acetonitrile (CAS 88757-52-2), molecular formula C11H6BrClN2O and molecular weight 297.54 g/mol, is a CATO reference standard with documented purity and traceability.

2-((5-Bromo-7-chloroquinolin-8-yl)oxy)acetonitrile (C11H6BrClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

As a certified reference material (CRM), 2-((5-Bromo-7-chloroquinolin-8-yl)oxy)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H6BrClN2O
Molecular Weight297.54 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1982
Halogen ContentCl/Br-containing
Nitrogen Atoms2

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