Dotinurad Impurity 136 CAS 1285572-83-9
| CAS No. | 1285572-83-9 |
| Molecular Formula | C14H9ClFNO4S |
| Molecular Weight | 341.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Dotinurad Impurity 136 (C14H9ClFNO4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Dotinurad Impurity 136 (CAS 1285572-83-9) is a certified pharmaceutical impurity reference standard with the molecular formula C14H9ClFNO4S and a molecular weight of 341.74 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dotinurad Impurity 136 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9ClFNO4S |
| Molecular Weight | 341.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dotinurad Standards
- Dotinurad Impurity 3 (CAS 1285572-55-5)
- Dotinurad Impurity 35 (CAS CATO-C4X-249435)
- Dotinurad Impurity 163 (CAS CATO-C4X-2494163)
- Dotinurad Impurity 10 (CAS 1285573-42-3)
- Dotinurad Impurity 38 (CAS CATO-C4X-249438)
- Dotinurad Impurity 30 (CAS CATO-C4X-249430)
- Dotinurad Impurity 191 (CAS CATO-C4X-2494191)
- Dotinurad Impurity 166 (CAS CATO-C4X-2494166)
Recommended Standards
- N-(3-Chloro-4-methylphenyl)-2,2-difluoro-2-(4-methoxyphenoxy)acetamide (CAS 303151-13-5)
- (2-Chlorophenyl)(3-(3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl)azetidin-1-yl)methanone (CAS 1323707-27-2)
- N-(3-chloro-2-methylphenyl)-2,2-difluoro-2-(4-methoxyphenoxy)acetamide (CAS 303151-17-9)
- (3R,4R,5R)-3-Allyl-2-(2-amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 1378912-51-6)
- Nicergoline Impurity 20 (CAS CATO-C4X-208520)
- Quetiapine Impurity 85 (CAS 141691-24-9)
- Aceclofenac Impurity 11 (CAS 2517857-21-3)
- 6-(Indolin-1-yl)-5-methylnicotinonitrile (CAS 1355232-64-2)
- 2-(5-Chloro-1-methyl-1h-imidazol-2-yl)ethanethioamide (CAS 1211349-15-3)
- 2-(4-Ethoxy-2,3-difluorophenyl)acetonitrile (CAS 1017779-59-7)
- 2,4,6-Triisopropyl-1,3,5,2,4,6-trioxatriborinane (CAS 66740-05-4)
- 1-(5-Chloro-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (CAS 937591-81-6)
- 2-(Thiophen-2-yl)benzonitrile (CAS 125610-77-7)
- Neuropeptide Y (22-36) (CAS 119019-65-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com