Dotinurad Impurity 166 CAS CATO-C4X-2494166
| CAS No. | CATO-C4X-2494166 |
| Molecular Formula | C16H14ClNO3S |
| Molecular Weight | 335.81 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Dotinurad Impurity 166 (CAS CATO-C4X-2494166), a pharmacopoeial impurity reference standard (molecular formula C16H14ClNO3S, MW 335.81 g/mol) used for the identification and quantification of trace impurities in APIs.
Dotinurad Impurity 166 (C16H14ClNO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dotinurad Impurity 166 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H14ClNO3S |
| Molecular Weight | 335.81 g/mol |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dotinurad Standards
- Dotinurad Impurity 30 (CAS CATO-C4X-249430)
- Dotinurad Impurity 178 (CAS CATO-C4X-2494178)
- Dotinurad Impurity 218 (CAS CATO-C4X-2494218)
- Dotinurad Impurity 38 (CAS CATO-C4X-249438)
- Dotinurad Impurity 10 (CAS 1285573-42-3)
- Dotinurad Impurity 233 (CAS CATO-C4X-2494233)
- Dotinurad Impurity 181 (CAS 425666-79-1)
- Dotinurad Impurity 219 (CAS CATO-C4X-2494219)
Recommended Standards
- n-(4-Chlorophenyl)-5-methyl-N-(4-methyl-4,5-dihydro-1,3-thiazol-2-yl)-1,2-oxazole-3-carboxamide (CAS 870760-07-9)
- Abemaciclib Impurity 123 (CAS CATO-C4X-2937123)
- N-(4-chlorophenyl)-2-((phenylsulfonyl)methyl)acrylamide (CAS 400074-36-4)
- 3-Chloro-N-[2-(2-ethoxyethoxy)benzyl]-4-methoxyaniline (CAS 1040685-88-8)
- Iopromide Impurity 19 (CAS CATO-C4X-183219)
- Otilonium Bromide Impurity 4 (CAS 1007652-84-7)
- Morantel impurity 1 (CAS CATO-C4X-30741)
- 3-(Piperazin-1-yl)phenol dihydrochloride (CAS 807624-37-9)
- Methyl 2-(2-(2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl)hydrazinyl)-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 648427-12-7)
- 3-aminopyridine 1-oxide Hydrochloride (CAS 65600-69-3)
- N-(2-Ethylphenyl)-2-((4-oxo-3-propyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1252988-63-8)
- 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine dihydrochloride (CAS 2096336-57-9)
- 2-Hydroxy-5-Chlorobiphenyl (CAS 607-12-5)
- D-Ala28-Tirzepatide (CAS CATO-CPTD788906)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com