Dotinurad Impurity 1 CAS 1285573-44-5
| CAS No. | 1285573-44-5 |
| Molecular Formula | C15H11Cl2NO4S |
| Molecular Weight | 372.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 372.22 g/mol gives Dotinurad Impurity 1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Dotinurad Impurity 1 (CAS 1285573-44-5, C15H11Cl2NO4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Dotinurad Impurity 1 (C15H11Cl2NO4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dotinurad Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11Cl2NO4S |
| Molecular Weight | 372.22 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dotinurad Standards
- Dotinurad Impurity 124 (CAS 888730-55-0)
- Dotinurad Impurity 14 (CAS CATO-C4X-249414)
- Dotinurad Impurity 248 (CAS CATO-C4X-2494248)
- Dotinurad Impurity 161 (CAS CATO-C4X-2494161)
- Dotinurad Impurity 222 (CAS CATO-C4X-2494222)
- Dotinurad Impurity 66 (CAS CATO-C4X-249466)
- Dotinurad Impurity 5 (CAS 1285572-89-5)
- Dotinurad Impurity 131 (CAS CATO-C4X-2494131)
Recommended Standards
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- 1-(6-Amino-3,4-dihydroquinolin-1(2H)-yl)ethanone (CAS 27392-71-8)
- Ethyl 2-(1-aminoethyl)-4-methyl-1,3-thiazole-5-carboxylate (CAS 1017469-56-5)
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- Semaglutide impound 212 (CAS CATO-C4X-2226212)
Why CATO?
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