Foritinib Impurity 1 CAS CATO-C4X-33101
| CAS No. | CATO-C4X-33101 |
| Molecular Formula | C20H24N2O3 |
| Molecular Weight | 340.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Foritinib Impurity 1 (CAS CATO-C4X-33101) is a certified pharmaceutical impurity reference standard with the molecular formula C20H24N2O3 and a molecular weight of 340.42 g/mol.
Structurally, Foritinib Impurity 1 (C20H24N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 340.42 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Foritinib Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H24N2O3 |
| Molecular Weight | 340.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Foritinib Standards
- Foritinib Impurity 8 (CAS CATO-C4X-33108)
- Foritinib Impurity 13 (CAS CATO-C4X-331013)
- Foritinib Impurity 14 (CAS CATO-C4X-331014)
- Foritinib Impurity 5 (CAS CATO-C4X-33105)
- Foritinib Impurity 9 (CAS CATO-C4X-33109)
- Foritinib Impurity 17 (CAS CATO-C4X-331017)
- Foritinib Impurity 2 (CAS CATO-C4X-33102)
- Foritinib Impurity 16 (CAS CATO-C4X-331016)
Recommended Standards
- Peficitinib Impurity 23 (CAS 2055576-50-4)
- Peficitinib Impurity 13 (CAS 944118-04-1)
- (3R)-3-Hydroxy Quinine (CAS 128241-59-8)
- Quinidine N-Oxide (CAS 70116-00-6)
- Icaritin Impurity 7 (CAS 60-82-2)
- Sivelestat Impurity 33 (CAS CATO-C4X-212333)
- Fluconazole Impurity 7 (CAS 173837-65-5)
- 4-Chloro-5-(4-chlorophenyl)nicotinonitrile (CAS 1710661-24-7)
- CAS CATO-C4X-125476 (CAS CATO-C4X-125476)
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- S-(4,5-Dihydrothiazol-2-yl) ethanethioate (CAS 408331-56-6)
- 1-Bromo-4-chloro-6,7-dihydro-5H-cyclopenta[c]pyridine (CAS 2762659-25-4)
- 4-Ethoxy-N-(3-methoxypropyl)benzenesulfonamide (CAS 676643-24-6)
- Acetyl Tetrapeptide- 15 (CAS 928007-64-1)
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