2-Chloro-1-(7-nitro-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)ethan-1-one CAS 128627-29-2
| CAS No. | 128627-29-2 |
| Molecular Formula | C10H9ClN2O4 |
| Molecular Weight | 256.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-1-(7-nitro-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)ethan-1-one.
2-Chloro-1-(7-nitro-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)ethan-1-one (CAS 128627-29-2) is a high-purity analytical reference standard with the molecular formula C10H9ClN2O4 and a molecular weight of 256.64 g/mol.
The molecular framework of 2-Chloro-1-(7-nitro-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)ethan-1-one (C10H9ClN2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-1-(7-nitro-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9ClN2O4 |
| Molecular Weight | 256.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
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- 1-(5-Chlorothiophen-2-yl)-4,4,4-trifluorobutane-1,3-dione (CAS 326-73-8)
- Ethyl 2-ethoxymethylene-4,4-difluoro-4-chloroacetoacetate (CAS 182551-59-3)
- 1-bromo-2,3-dimethoxypropane (CAS 90321-40-7)
- Benzyl (R)-1,2-dimethylpyrrolidine-2-carboxylate (CAS 1268521-48-7)
- 3-Chloro-2-piperidinomethyl benzophenone (CAS 898773-09-6)
- Mal-NH-PEG8-CH2CH2COOPFP ester (CAS 2055023-14-6)
- 2-(4-(3-(3-Nitrophenyl)-1H-pyrazol-5-yl)piperidin-1-yl)nicotinonitrile (CAS 1030386-17-4)
- Roxatidine Impurity 46 (CAS 4764-13-0)
- 2-(Pyridin-4-ylmethoxy)acetic acid hydrochloride hydrate (CAS 1452518-57-8)
- 4-(((3-Fluorophenyl)thio)methyl)piperidine hydrochloride (CAS 1353963-00-4)
- 2-(2-Phenylacetamido)ethyl 3-oxobutanoate (CAS 92246-33-8)
- D-Pro31-Tirzepatide (CAS CATO-CPTD788905)
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