tert-Butyl 1-(3-fluoro-2-methylbenzyl)piperidin-4-ylcarbamate CAS 1286275-70-4
| CAS No. | 1286275-70-4 |
| Molecular Formula | C18H27FN2O2 |
| Molecular Weight | 322.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies tert-Butyl 1-(3-fluoro-2-methylbenzyl)piperidin-4-ylcarbamate (CAS 1286275-70-4), a certified reference material (molecular formula C18H27FN2O2, MW 322.42 g/mol) for analytical method development and quality control.
The molecular framework of tert-Butyl 1-(3-fluoro-2-methylbenzyl)piperidin-4-ylcarbamate (C18H27FN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures tert-Butyl 1-(3-fluoro-2-methylbenzyl)piperidin-4-ylcarbamate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H27FN2O2 |
| Molecular Weight | 322.42 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl (1R*,4R*)-4-(2-fluorobenzylamino)cyclohexylcarbamate (CAS 1286275-00-0)
- (3-Amino-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridin-2-yl)(phenyl)methanone (CAS 130506-75-1)
- Tert-butyl (4-((3-fluorobenzyl)amino)cyclohexyl)carbamate (CAS 1286274-76-7)
- tert-Butyl 4-((4-fluoro-2-methylbenzyl)amino)piperidine-1-carboxylate (CAS 1349715-60-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com