4-(3-Phenylpropoxy)-3-(trifluoromethyl)aniline CAS 946775-60-6

Purity 97%+In StockPharmaceutical Standards
CAS No.946775-60-6
Molecular FormulaC16H16F3NO
Molecular Weight295.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(3-Phenylpropoxy)-3-(trifluoromethyl)aniline CAS 946775-60-6 chemical structure

Description

4-(3-Phenylpropoxy)-3-(trifluoromethyl)aniline (CAS 946775-60-6), molecular formula C16H16F3NO and molecular weight 295.30 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-(3-Phenylpropoxy)-3-(trifluoromethyl)aniline (C16H16F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(3-Phenylpropoxy)-3-(trifluoromethyl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H16F3NO
Molecular Weight295.30 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms1

Related Phenylpropoxy Standards

Recommended Standards

Why CATO?