4-tert-Butyldimethylsilyloxy-6-fluoro-2-formyl-3,4-dihydro-2H-1-benzopyran CAS 1286400-05-2
| CAS No. | 1286400-05-2 |
| Molecular Formula | C16H23FO3Si |
| Molecular Weight | 310.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-tert-Butyldimethylsilyloxy-6-fluoro-2-formyl-3,4-dihydro-2H-1-benzopyran (C16H23FO3Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 4-tert-Butyldimethylsilyloxy-6-fluoro-2-formyl-3,4-dihydro-2H-1-benzopyran (CAS 1286400-05-2), a certified reference material (molecular formula C16H23FO3Si, MW 310.44 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-tert-Butyldimethylsilyloxy-6-fluoro-2-formyl-3,4-dihydro-2H-1-benzopyran under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H23FO3Si |
| Molecular Weight | 310.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related tert Standards
- 1286156-10-2 4-tert-Butyldimethylsilyloxy-6-fluoro-2-hydroxymethyl-3,4-dihydro-2H-1-benzopyran (Mixture of Diastereomers) (CAS 1286156-10-2)
- 2-((tert-Butyldimethylsilyloxy)methyl)-6-chlorofuro[3,2-b]pyridine (CAS 1171920-42-5)
- 2-((tert-Butyldimethylsilyloxy)methyl)furo[3,2-b]pyridine-6-carboxylic acid (CAS 1171920-49-2)
- 3-(t-Butyldimethylsilyloxy)-4-chloro-2-fluorophenylboronic acid (CAS 1256354-94-5)
- 4-(tert-Butyldimethylsilyloxy)-3-chloro-2-fluorophenylboronic acid (CAS 2377608-26-7)
- 2-(t-Butyldimethylsilyloxy)-4-bromoanisole (CAS 177329-71-4)
- 4-[2-(tert-Butyldimethylsilyloxy)ethyl]-3-fluorophenylboronic acid (CAS 2377606-02-3)
- 1286582-56-6 4-tert-Butyldimethylsilyloxy-6-fluoro-2-oxiranyl-3,4-dihydro-2H-1-benzopyran (Mixture of Diastereomers) (CAS 1286582-56-6)
Recommended Standards
- 2-Amino-2-(((S)-1-oxo-1-(pyrrolidin-1-yl)butan-2-yl)amino)-1-(pyrrolidin-1-yl)butan-1-one (CAS 1152110-34-3)
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- 1-(Allyloxy)-5-chloro-4-methoxy-2-nitrobenzene (CAS 1407532-81-3)
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- Semaglutide Impurity 5 (CAS 23406-82-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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