4-(tert-Butyldimethylsilyloxy)-3-chloro-2-fluorophenylboronic acid CAS 2377608-26-7
| CAS No. | 2377608-26-7 |
| Molecular Formula | C12H19BClFO3Si |
| Molecular Weight | 304.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-(tert-Butyldimethylsilyloxy)-3-chloro-2-fluorophenylboronic acid (CAS 2377608-26-7), a certified reference material (molecular formula C12H19BClFO3Si, MW 304.63 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H19BClFO3Si, 4-(tert-Butyldimethylsilyloxy)-3-chloro-2-fluorophenylboronic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 304.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 4-(tert-Butyldimethylsilyloxy)-3-chloro-2-fluorophenylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H19BClFO3Si |
| Molecular Weight | 304.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.5 |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
Related tert Standards
- 3-(t-Butyldimethylsilyloxy)-4-chloro-2-fluorophenylboronic acid (CAS 1256354-94-5)
- 2-((tert-Butyldimethylsilyloxy)methyl)-6-chlorofuro[3,2-b]pyridine (CAS 1171920-42-5)
- 4-tert-Butyldimethylsilyloxy-6-fluoro-2-formyl-3,4-dihydro-2H-1-benzopyran (CAS 1286400-05-2)
- 4-[2-(tert-Butyldimethylsilyloxy)ethyl]-3-fluorophenylboronic acid (CAS 2377606-02-3)
- 1286156-10-2 4-tert-Butyldimethylsilyloxy-6-fluoro-2-hydroxymethyl-3,4-dihydro-2H-1-benzopyran (Mixture of Diastereomers) (CAS 1286156-10-2)
- 2-((tert-Butyldimethylsilyloxy)methyl)furo[3,2-b]pyridine-6-carboxylic acid (CAS 1171920-49-2)
- 2-(t-Butyldimethylsilyloxy)-4-bromoanisole (CAS 177329-71-4)
- 1076199-67-1 3-(tert-Butyldimethylsilyloxy)-5-(1-methylamino)-5-oxopentanoic Acid Methyl Ester 3-[(1,1-Dimethylethyl)dimethylsilyloxy]-5-(1-methylamino)-5-oxopentanoic Acid Methyl Ester (CAS 1076199-67-1)
Recommended Standards
- 3-[(tert-Butyldimethylsilyl)oxy]-2-chloro-6-fluorophenylboronic acid (CAS 2377611-81-7)
- 5-(Chlorosulfonyl)-2-(trifluoromethoxy)benzoic acid (CAS 845616-29-7)
- [Pd(acac)<SUB>2</SUB>] (CAS 14024-61-4)
- 2,2,3,3,9,9,10,10-Octamethyl-4,8-dioxa-3,9-disilaundecane (CAS 82112-22-9)
- 1-(4-Amino-1h-pyrazol-1-yl)-3-[methoxy(methyl)amino]propan-2-ol (CAS 1154213-77-0)
- (3-Chloro-5-fluorophenyl)(cyclopentyl)methanone (CAS 898791-72-5)
- 1-Boc-3-bromo-5-methylindole (CAS 914349-24-9)
- 2-Amino-N-methyl-2-phenyl-N-(tetrahydro-2H-pyran-4-yl)acetamide (CAS 1218323-36-4)
- 2-(4-Hydroxy-3,5-dimethylphenyl)-7-methyl-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(1H)-one (CAS 2118944-88-8)
- tert-Butyl ((1-(6-ethoxy-2-(methylthio)pyrimidin-4-yl)piperidin-4-yl)methyl)carbamate (CAS 1353958-12-9)
- 2,5-Dichloro-N-[5,6-dimethyl-1-(propan-2-yl)-1H-1,3-benzodiazol-4-yl]benzene-1-sulfonamide (CAS 338423-22-6)
- 1,2,2,2-Tetrafluoroethyl trifluoromethyl ether (CAS 2356-62-9)
- 3-methoxy-4-carboxyphenylboronic acid (CAS 851335-12-1)
- Gastrin Tetrapeptide (CAS 1947-37-1)
Why CATO?
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