Methyl 2-chloro-4-methyl-3-oxo-2,3-dihydrothiophene-2-carboxylate CAS 128775-88-2
| CAS No. | 128775-88-2 |
| Molecular Formula | C7H7ClO3S |
| Molecular Weight | 206.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Methyl 2-chloro-4-methyl-3-oxo-2,3-dihydrothiophene-2-carboxylate (CAS 128775-88-2), molecular formula C7H7ClO3S and molecular weight 206.65 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 2-chloro-4-methyl-3-oxo-2,3-dihydrothiophene-2-carboxylate (C7H7ClO3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7ClO3S |
| Molecular Weight | 206.65 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
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- N-[3-(Trifluoromethyl)phenyl]-4-{4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}benzamide (CAS 321430-21-1)
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- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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