1,3-Diethyl 2-{[(2-benzoyl-4-chlorophenyl)amino]methylidene}propanedioate CAS 128832-34-8
| CAS No. | 128832-34-8 |
| Molecular Formula | C21H20ClNO5 |
| Molecular Weight | 401.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1,3-Diethyl 2-{[(2-benzoyl-4-chlorophenyl)amino]methylidene}propanedioate (C21H20ClNO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1,3-Diethyl 2-{[(2-benzoyl-4-chlorophenyl)amino]methylidene}propanedioate (CAS 128832-34-8), molecular formula C21H20ClNO5 and molecular weight 401.84 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,3-Diethyl 2-{[(2-benzoyl-4-chlorophenyl)amino]methylidene}propanedioate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H20ClNO5 |
| Molecular Weight | 401.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Diethyl Standards
- Diethyl 5-(benzofuran-2-carboxamido)-3-methylthiophene-2,4-dicarboxylate (CAS 301304-89-2)
- 1,3-Diethyl 2-[2-nitro-1-(3-phenoxyphenyl)ethyl]propanedioate (CAS 866153-01-7)
- Diethyl 2-(3-(benzyloxy)propyl)-2-(4-fluorophenyl)malonate (CAS 1523572-00-0)
- Diethyl 3,3'-(disulfanediylbis(methylene))bis(5-methylisoxazole-4-carboxylate) (CAS 296266-52-9)
- Diethyl ((4-bromo-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)methyl)phosphonate (CAS 54813-89-7)
- Diethyl 2-(((4-iodo-2-methylphenyl)-amino)methylene)malonate (CAS 951006-38-5)
- Diethyl [2,2'-biquinoline]-4,4'-dicarboxylate (CAS 912-84-5)
- Diethyl (2-(4-(benzyloxy)phenyl)-1,1-difluoro-2-hydroxyethyl)phosphonate (CAS 181059-93-8)
Recommended Standards
- Triasulfuron (CAS 82097-50-5)
- 2-(1-(2-Chloroacetyl)-3-oxopiperazin-2-yl)-N-(4-phenoxyphenyl)acetamide (CAS 1306738-30-6)
- Methyl 2-(3-(2-chlorobenzyl)-5-cyano-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)thiophene-3-carboxylate (CAS 343374-95-8)
- Alvocidib (Flavopiridol) (CAS 146426-40-6)
- 4-(3-Cyano-pyrazin-2-yl)-benzoic acid ethyl ester (CAS 1208081-68-8)
- 3-(2,4-Dimethoxyphenyl)pentan-3-ol (CAS 876291-08-6)
- 1,2-Bis((2S,5S)-2,5-di-i-propylphospholano)ethane(cyclooctadiene)rhodium(I) tetrafluoroborate (CAS 213343-67-0)
- Benzyl 4-(((3,4-dimethylphenyl)amino)methyl)-4-hydroxypiperidine-1-carboxylate (CAS 1353878-05-3)
- 2-(4-Methyl-1H-pyrazol-1-yl)propanamide (CAS 1255147-64-8)
- Vonoprazan Impurity 187 (CAS 2067322-23-8)
- Tert-butyl 4-((methylamino)methyl)piperidine-1-carboxylate but-2-enedioate (CAS 1423796-07-9)
- 1-(6-Bromohexyl)-1,2,4-triazole (CAS 1227481-33-5)
- (1S,2S,5S)-Ethyl [(2-Hydroxypinan-3-ylene)amino]acetate (CAS 90473-00-0)
- Tumor Targeted Pro-Apoptotic Peptide (CAS 1926163-30-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com