Alvocidib (Flavopiridol) CAS 146426-40-6
| CAS No. | 146426-40-6 |
| Molecular Formula | C21H20ClNO5 |
| Molecular Weight | 401.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Alvocidib (Flavopiridol) (CAS 146426-40-6), molecular formula C21H20ClNO5 and molecular weight 401.84 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Alvocidib (Flavopiridol) (C21H20ClNO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Alvocidib (Flavopiridol) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H20ClNO5 |
| Molecular Weight | 401.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-(1-(2-Chloroacetyl)-3-oxopiperazin-2-yl)-N-(4-phenoxyphenyl)acetamide (CAS 1306738-30-6)
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- 1,3-Diethyl 2-{[(2-benzoyl-4-chlorophenyl)amino]methylidene}propanedioate (CAS 128832-34-8)
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- 4,8-Dichloro-6-fluoroquinoline (CAS 1019016-95-5)
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- (S)-2-(4-bromophenyl)-2-(methylamino)ethan-1-ol (CAS 1213389-54-8)
- 1-(5-Aminobenzofuran-2-yl)ethan-1-one (CAS 27408-34-0)
- Semaglutide Impurity 129 (CAS 2490269-79-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com