2-Formyl-6-(trifluoromethyl)nicotinic acid CAS 1289132-83-7
| CAS No. | 1289132-83-7 |
| Molecular Formula | C8H4F3NO3 |
| Molecular Weight | 219.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Formyl-6-(trifluoromethyl)nicotinic acid.
2-Formyl-6-(trifluoromethyl)nicotinic acid (CAS 1289132-83-7), molecular formula C8H4F3NO3 and molecular weight 219.12 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Formyl-6-(trifluoromethyl)nicotinic acid (C8H4F3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 219.12 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4F3NO3 |
| Molecular Weight | 219.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Formyl Standards
- 4-Formyl-6-(trifluoromethyl)picolinic acid (CAS 1289075-03-1)
- 3-Formyl-5-methoxy-1h-indole-2-carboxylic acid (CAS 57646-80-7)
- 3-Formyl-6-methoxy-1h-indole-2-carboxylic acid (CAS 858752-19-9)
- Methyl 6-formyl-7-methyl-7H-pyrrolo[2,3-d]pyrimidine-2-carboxylate (CAS 1823530-02-4)
- 4-(5-Formyl-2-methoxyphenoxy)butanenitrile (CAS 1016842-76-4)
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- 3-Formyl-5-methylbenzenesulfonyl chloride (CAS 1393546-56-9)
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Recommended Standards
- 5-bromo-6-methylimidazo[1,2-a]pyridine (CAS 1346157-13-8)
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- 3-bromo-1-methyl-pyrrolo[3,2-b]pyridine (CAS 1357142-80-3)
- 7-bromo-3-methyl-imidazo[1,2-a]pyridine (CAS 1276026-68-6)
- 2-Hydroxy-N-(2-methyl-4-nitrophenyl)acetamide (CAS 926271-43-4)
- Methyl 3-acetyl-4,5-dihydroisoxazole-4-carboxylate (CAS 132659-36-0)
- ((1R,2R,3S,5R)-2-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-3-yl)methanol (CAS 327611-76-7)
- Methoxamine Impurity 16 (CAS 121347-31-7)
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- 2,5-Dichlorobenzotrifluoride (CAS 320-50-3)
- 2-(phenothiazin-3-ylideneamino)benzene-1,4-disulfonic acid (CAS 178861-30-8)
- tert-butyl 3-oxo-2,3-dihydro-1H-pyrazole-1-carboxylate (CAS 2088458-39-1)
- 2-((2-Ethylpiperidin-1-yl)sulfonyl)aniline (CAS 866152-73-0)
- Mast Cell Degranulating (MCD) Peptide HR-2 (CAS 80388-04-1)
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