2-Chloro-6-fluorobenzyl 1-(2-chloro-6-fluorobenzyl)azetidine-3-carboxylate CAS 1289385-42-7
| CAS No. | 1289385-42-7 |
| Molecular Formula | C18H15Cl2F2NO2 |
| Molecular Weight | 386.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Chloro-6-fluorobenzyl 1-(2-chloro-6-fluorobenzyl)azetidine-3-carboxylate (CAS 1289385-42-7) is a high-purity analytical reference standard with the molecular formula C18H15Cl2F2NO2 and a molecular weight of 386.22 g/mol.
Structurally, 2-Chloro-6-fluorobenzyl 1-(2-chloro-6-fluorobenzyl)azetidine-3-carboxylate (C18H15Cl2F2NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 386.22 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H15Cl2F2NO2 |
| Molecular Weight | 386.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3,3-Bis(5-chloro-2-hydroxyphenyl)indolin-2-one (CAS 855423-75-5)
- 3-Chloro-4-(3-(4-chlorophenyl)-5-oxoimidazolidin-1-yl)benzenesulfonamide (CAS 53298-04-7)
- 4-Chloro-3-[[(2-chlorophenyl)-2-propen-1-ylamino]sulfonyl]benzoic acid (CAS 380436-74-8)
- 2-Chloro-N'-[6-chloro-4-(trifluoromethyl)pyridin-2-yl]benzene-1-sulfonohydrazide (CAS 1790211-83-4)
- [4-(3-Chloro-phenyl)-[1,3,5]triazin-2-yl]-(6-chloro-4-trifluoromethyl-pyridin-2-yl)-amine (CAS 1311278-30-4)
- (4-Chloro-phenyl)-[5-(3-chloro-5-trifluoromethyl-pyridin-2-yl)-pyrazol-1-yl]-methanone (CAS 1311278-51-9)
- (2E)-3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-chlorophenyl)-2-cyanoprop-2-enamide (CAS 338978-46-4)
- 4-Chloro-2-ethylpyridine (CAS 3678-65-7)
Recommended Standards
- Apremilast Impurity 99 (CAS CATO-C4X-100999)
- 3-(3-Bromo-4-methoxy-phenylsulfamoyl)-benzoic acid (CAS 568551-62-2)
- 4,4,5,5-Tetramethyl-2-(3-((tetrahydro-2h-pyran-4-yl)methoxy)-5-(trifluoromethyl)phenyl)-1,3,2-dioxaborolane (CAS 2096330-34-4)
- 3-[(4-bromophenyl)sulfamoyl]-4-methoxybenzoic acid (CAS 312274-98-9)
- Ethyl (S)-7-amino-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-b]pyridine-3-carboxylate (CAS 2792173-69-2)
- 2-Methyl-2-(methylamino)-4-(1h-pyrazol-1-yl)butanamide (CAS 1248761-86-5)
- 5-(2,5-Dichlorophenyl)isoxazol-3-amine (CAS 1488891-85-5)
- 1-(1-Bromonaphthalen-2-yl)cyclopropan-1-amine (CAS 1704135-98-7)
- Benzyl ((1-((S)-2-aminopropanoyl)piperidin-3-yl)methyl)(cyclopropyl)carbamate (CAS 1354033-39-8)
- 5-(3,5-Dimethoxyphenyl)-5-oxopentanoic acid (CAS 898792-55-7)
- 5-aminothiophene-2-carbonitrile (CAS 52532-63-5)
- 1-(5-bromo-1H-indol-3-yl)ethan-1-ol (CAS 1553992-62-3)
- TPD48-2Br (CAS 1262241-50-8)
- Semaglutide impurity 92 (CAS CATO-C4X-222692)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com