(2E)-3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-chlorophenyl)-2-cyanoprop-2-enamide CAS 338978-46-4
| CAS No. | 338978-46-4 |
| Molecular Formula | C16H8Cl2F3N3O |
| Molecular Weight | 386.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (2E)-3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-chlorophenyl)-2-cyanoprop-2-enamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
(2E)-3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-chlorophenyl)-2-cyanoprop-2-enamide (CAS 338978-46-4) is a high-purity analytical reference standard with the molecular formula C16H8Cl2F3N3O and a molecular weight of 386.16 g/mol.
Based on its molecular formula C16H8Cl2F3N3O, (2E)-3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-chlorophenyl)-2-cyanoprop-2-enamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 386.16 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H8Cl2F3N3O |
| Molecular Weight | 386.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related E Standards
- [4-(3-Chloro-phenyl)-[1,3,5]triazin-2-yl]-(6-chloro-4-trifluoromethyl-pyridin-2-yl)-amine (CAS 1311278-30-4)
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Recommended Standards
- (2,4-Dichlorophenyl)(1-(2-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-4-yl)methanone (CAS 477847-85-1)
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- 4-((3-Fluorobenzyl)oxy)-3-iodobenzohydrazide (CAS 1706458-42-5)
- 4-((2-Fluorobenzyl)oxy)-3-iodo-5-methoxybenzaldehyde (CAS 428847-21-6)
- methyl 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate (CAS 1638760-75-4)
- 2-(Pyrrolidin-1-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1259445-03-8)
- 2-Hydroxy-3-nitro-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 56517-41-0)
- Peramivir Impurity 133 (CAS CATO-C4X-1833133)
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- 6-Chlorobenzo[d]isoxazole-3-carbonitrile (CAS 52046-83-0)
- 2-(3-Methyl-5-thioxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)acetic acid (CAS 42047-33-6)
- Semaglutide Main Chain P29 (CAS 1169630-82-3)
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