(R)-4,6-Dimethyl-N-(pyrrolidin-3-yl)pyrimidin-2-amine hydrochloride CAS 1289584-90-2
| CAS No. | 1289584-90-2 |
| Molecular Formula | C10H16N4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (R)-4,6-Dimethyl-N-(pyrrolidin-3-yl)pyrimidin-2-amine hydrochloride (C10H16N4HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies (R)-4,6-Dimethyl-N-(pyrrolidin-3-yl)pyrimidin-2-amine hydrochloride (CAS 1289584-90-2), a certified reference material (molecular formula C10H16N4HCl, MW 228.72 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H16N4 HCl |
| Molecular Weight | 228.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related R Standards
- 2,4-dimethyl-1,3-pentadiene (CAS 1000-86-8)
- 2-(2,6-Dimethyl-5-nitropyrimidin-4-yl)phenol (CAS 100008-90-0)
- 1,3-dimethyl-5,8-dihydropyrido[2,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione (CAS 10001-46-4)
- 3-(6,8-Dimethyl-[1,2,4]triazolo[4,3-b]pyridazin-7-yl)-propionic acid (CAS 1000339-20-7)
- 6,7-Dimethyl-3-formyl (1H)indazole (CAS 1000340-59-9)
- 6,7-Dimethyl-1H-indazole-3-carboxylic acid (CAS 1000340-61-3)
- 4,7-Dimethyl-1h-indazole-3-carbaldehyde (CAS 1000340-75-9)
- 4,7-Dimethyl-1h-indazole-3-carboxylic acid (CAS 1000340-77-1)
Recommended Standards
- (R)-SunPhos (CAS 765312-57-0)
- 6-(3-(Pyrrolidin-1-ylsulfonyl)phenyl)pyridin-3-ol (CAS 1261975-28-3)
- 3-(2-Methoxy-2-oxoethyl)phenylboronic Acid Pinacol Ester (CAS 478375-42-7)
- 4-Bromo-2-fluoro-5-iodobenzoic acid (CAS 1521585-65-8)
- Empagliflozin impurity 236 (CAS 2069942-68-1)
- 17-Hydroxyventuricidin A (CAS 113204-43-6)
- 2,4,6-triisopropylbenzenesulfonyl chloride (CAS CATO-C4X-33637)
- 6-Bromo-2-methyl-1,2,3,4-tetrahydroquinoline (CAS 42835-98-3)
- 2-(2-Methyl-1,3-dioxan-2-yl)ethan-1-amine (CAS 218602-40-5)
- Exenatide (CAS 141758-74-9（free base）)
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