Mebendazole EP Impurity G CAS 129165-82-8
| CAS No. | 129165-82-8 |
| Molecular Formula | C29H20N6O3 |
| Molecular Weight | 500.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Mebendazole EP Impurity G (CAS 129165-82-8) is a certified pharmaceutical impurity reference standard with the molecular formula C29H20N6O3 and a molecular weight of 500.51 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Mebendazole EP Impurity G is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 500.51 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Mebendazole EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H20N6O3 |
| Molecular Weight | 500.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 23.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 6 |
Related Mebendazole Standards
- Mebendazole impurity 3 (CAS CATO-C4X-27683)
- Mebendazole EP Impurity E (CAS 31430-19-0)
- Mebendazole EP Impurity F (CAS 31545-31-0)
- Mebendazole EP Impurity D (CAS 132119-11-0)
- Mebendazole D3 (CAS 1173021-87-8)
- Mebendazole Impurity 14 (CAS 104663-13-0)
- Mebendazole (CAS 31431-39-7)
- Mebendazole EP Impurity C (CAS 66066-76-0)
Recommended Standards
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