4-[(E)-2-[(2,4-Dichlorophenyl)methylidene]hydrazin-1-yl]quinazoline CAS 129177-08-8
| CAS No. | 129177-08-8 |
| Molecular Formula | C15H10Cl2N4 |
| Molecular Weight | 317.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[(E)-2-[(2,4-Dichlorophenyl)methylidene]hydrazin-1-yl]quinazoline.
4-[(E)-2-[(2,4-Dichlorophenyl)methylidene]hydrazin-1-yl]quinazoline (CAS 129177-08-8), molecular formula C15H10Cl2N4 and molecular weight 317.17 g/mol, is a CATO reference standard with documented purity and traceability.
4-[(E)-2-[(2,4-Dichlorophenyl)methylidene]hydrazin-1-yl]quinazoline (C15H10Cl2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10Cl2N4 |
| Molecular Weight | 317.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related E Standards
- 2-(3,4-Dichlorophenyl)quinoline-8-carboxamide (CAS 655222-62-1)
- 3-(2,4-Dichlorophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 618098-88-7)
- 4-[(E)-2-[(3,4-Dichlorophenyl)methylidene]hydrazin-1-yl]quinazoline (CAS 339025-76-2)
- 4-[4-(2,4-Dichlorophenyl)pyrimidin-2-yl]phenol (CAS 477846-95-0)
- 5-(3,4-Dichlorophenyl)-2-oxo-N-propyloxazolidine-3-carboxamide (CAS 34725-09-2)
- 2-((3,4-Dichlorophenyl)thio)-5-fluorobenzoic acid (CAS 191154-43-5)
- 2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-5-methoxypyrimidin-4-ol (CAS 338955-80-9)
- 2-{[(3,4-dichlorophenyl)methyl]sulfanyl}-5-methoxypyrimidin-4-ol (CAS 339275-96-6)
Recommended Standards
- 3-Iodo-N-((tetrahydro-2h-pyran-4-yl)methyl)aniline (CAS 1274587-40-4)
- 2-Chloro-4-[(E)-2-[(4-chlorophenyl)methylidene]hydrazin-1-yl]quinazoline (CAS 129177-12-4)
- 2-((4-Iodophenoxy)methyl)piperidine (CAS 1247605-01-1)
- 4-[(3-Iodophenoxy)methyl]piperidine (CAS 1347292-97-0)
- 2-Amino-2-(6-methylpyridin-3-yl)ethanol (CAS 1270462-24-2)
- 2-(4-bromophenylsulfonamido)-4-methylpentanoic acid 2-([(4-Bromophenyl)sulfonyl]amino)-4-methylpentanoic acid 68305-78-2 (CAS 68305-78-2)
- (R,S)-Z-3-Amino-5-cyclohexyl-2-oxo-1,4-benzodiazepine (CAS 146373-94-6)
- 6-Bromo-2-chloro-8-methylquinolin-5-amine (CAS 858467-33-1)
- 2-Amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid (CAS 77521-29-0)
- 2-[3-(Benzyloxy)phenyl]thiophene (CAS 893736-12-4)
- 1-(4-Methylbenzoyl)piperazine (CAS 111752-26-2)
- (3S,5R,8S,9S,10S,13S,14R,17R)-3,17-dihydroxy-17-[(1R)-1-hydroxyethyl]-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one (CAS 13933-74-9)
- 1-(1,3,4-Thiadiazol-2-yl)azetidine-3-carboxylic acid (CAS 1343942-63-1)
- Endo-Gly4-Semaglutide (CAS CATO-C4X-222679)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com