2-Chloro-4-[(E)-2-[(4-chlorophenyl)methylidene]hydrazin-1-yl]quinazoline CAS 129177-12-4
| CAS No. | 129177-12-4 |
| Molecular Formula | C15H10Cl2N4 |
| Molecular Weight | 317.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-4-[(E)-2-[(4-chlorophenyl)methylidene]hydrazin-1-yl]quinazoline.
2-Chloro-4-[(E)-2-[(4-chlorophenyl)methylidene]hydrazin-1-yl]quinazoline (CAS 129177-12-4) is a high-purity analytical reference standard with the molecular formula C15H10Cl2N4 and a molecular weight of 317.17 g/mol.
Structurally, 2-Chloro-4-[(E)-2-[(4-chlorophenyl)methylidene]hydrazin-1-yl]quinazoline (C15H10Cl2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 317.17 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10Cl2N4 |
| Molecular Weight | 317.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 2-Chloro-4-[(E)-2-[(3-chlorophenyl)methylidene]hydrazin-1-yl]quinazoline (CAS 1815601-26-3)
- 1-Chloro-N-(4-chlorophenyl)isoquinoline-4-carboxamide (CAS 240799-58-0)
- 5-Chloro-3-(2-chlorophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 312311-47-0)
- 5-Chloro-3-(4-chlorophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 55828-85-8)
- 4-Chloro-6-[(4-chlorobenzenesulfonyl)methyl]-2-methylpyrimidine (CAS 339278-84-1)
- 2-Chloro-4-(2-chlorophenyl)-6-methyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 1707372-28-8)
- 2-Chloro-4-(4-chlorophenyl)-6-methyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 1710661-48-5)
- 1,2-Bis(2-chloro-5-methoxypyrimidin -4-yl)hydrazine (CAS 1956386-49-4)
Recommended Standards
- 4-[(E)-2-[(2,4-Dichlorophenyl)methylidene]hydrazin-1-yl]quinazoline (CAS 129177-08-8)
- 4-[(3-Iodophenoxy)methyl]piperidine (CAS 1347292-97-0)
- 3-Iodo-N-((tetrahydro-2h-pyran-4-yl)methyl)aniline (CAS 1274587-40-4)
- 2-(Cyclopropyl(2-iodobenzyl)amino)ethanol (CAS 1353959-47-3)
- 3,4,5,6-Tetrachloropicolinonitrile (CAS 17824-83-8)
- 1-(5-Bromo-3-fluoro-2-methylphenyl)ethan-1-one (CAS 2090849-51-5)
- N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-2-(3,5-dichlorophenoxy)acetamide (CAS 866154-53-2)
- 1-Methyl-6-phenyl-[1,2,4]triazolo[1,5-b][1,2,4]triazin-7(1H)-one (CAS 89569-72-2)
- 2-Chloro-5-ethyl-6-methyl-3-nitropyridine (CAS 139393-95-6)
- 5-Fluoro-2-(3-((R)-1-hydroxyethyl)-2,6-diisopropyl-5-propylpyridin-4-yl)phenol (CAS 1049703-56-1)
- N-((1-(Thiophen-3-ylmethyl)piperidin-4-yl)methyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide (CAS 1234808-44-6)
- 2-Amino-N-cyclopropyl-N-(((S)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)propanamide (CAS 1354024-97-7)
- Neuromedin N (CAS 92169-45-4)
- Insulin Glargine Metabolite M2 (CAS CATO-CPTD788867)
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