Ertugliflozin impurity 3 CAS 1298086-37-9
| CAS No. | 1298086-37-9 |
| Molecular Formula | C22H23ClO8 |
| Molecular Weight | 450.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 450.87 g/mol gives Ertugliflozin impurity 3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Ertugliflozin impurity 3 (CAS 1298086-37-9, C22H23ClO8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ertugliflozin impurity 3 (C22H23ClO8) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ertugliflozin impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H23ClO8 |
| Molecular Weight | 450.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
Related Ertugliflozin Standards
- Ertugliflozin impurity 10 (CAS 1689522-89-1)
- Ertugliflozin impurity 22 (CAS 1298086-28-8)
- Ertugliflozin Impurity 50 (CAS 1298086-33-5)
- Ertugliflozin Impurity 51 (CAS 1298086-34-6)
- Ertugliflozin impurity 8 (CAS 1528636-47-6)
- Ertugliflozin-d5 (CAS 1298086-22-2)
- Ertugliflozin impurity 24 (CAS CATO-C4X-301124)
- Ertugliflozin (CAS 1210344-57-2)
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